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How to get fromDenver to Mayo Clinic Hospitalby plane, bus, car, or bus (Greyhound)

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There are 8 ways to get from Denver to Mayo Clinic Hospital by plane, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Denver to Rochester

    best
    1. Fly from Denver (DEN) to Rochester (RST)plane plane DEN - RST
    6h 57m
    $90–410

  2. Bus

    1. Take the bus from Denver to Des Moinesbus bus
    2. Take the bus from Des Moines to Albert Leabus bus
    3. Take the bus from Albert Lea to Rochesterbus bus
    18h 35m

  3. Drive 831.5 mi

    1. Drive from Denver to Mayo Clinic Hospitalcar car 831.5 mi
    14h 14m
    $152–220

  4. Fly Denver to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Denver (DEN) to Minneapolis–Saint Paul International Airport (MSP)plane plane DEN - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 31m
    $172–392

  5. Fly Denver to Fort Dodge Municipal Airport, drive

    1. Fly from Denver (DEN) to Fort Dodge Municipal Airport (FOD)plane plane DEN - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Mayo Clinic Hospitalcar car
    6h 54m
    $105–420

  6. Bus to Colorado Springs Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Denver, CO to Colorado Springs, CObus bus
    2. Fly from Colorado Springs Airport (COS) to Minneapolis–Saint Paul International Airport (MSP)plane plane COS - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 10m
    $164–552

  7. Bus via Des Moines

    1. Take the bus from Denver Union Station to Des Moinesbus bus
    2. Take the bus from Des Moines to Albert Leabus bus
    3. Take the bus from Albert Lea to Rochesterbus bus
    19h 50m

  8. Bus via Omaha

    1. Take the bus from Denver to Omaha, NEbus bus
    2. Take the bus from Omaha to Des Moinesbus bus
    3. Take the bus from Des Moines to Albert Leabus bus
    4. Take the bus from Albert Lea to Rochesterbus bus
    20h 5m

Denver (DEN) to Rochester (RST) flights

Calendar44Weekly Planes
Duration4h 32mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Denver to Mayo Clinic Hospital.ExpandLaunch map view
  • Distance: 718.9 mi
  • Duration: 6h 57m

What companies run services between Denver, CO, USA and Mayo Clinic Hospital, MN, USA?

Delta, American Airlines, and two other airlines fly from Denver (DEN) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Denver to Mayo Clinic Hospital via Des Moines, Albert Lea, and Rochester in around 18h 35m.

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