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How to get fromDenver to San Diegoby plane, bus (Flixbus), bus, train, or car

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There are 6 ways to get from Denver to San Diego by plane, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Denver

    best
    1. Fly from Denver (DEN) to San Diego International Airport (SAN)plane plane DEN - SAN
    4h
    $130–220
  2. Bus to Colorado Springs Airport, fly

    cheapest
    1. Take the bus from Denver, CO to Colorado Springs, CObus bus
    2. Fly from Colorado Springs Airport (COS) to San Diego International Airport (SAN)plane plane COS - SAN
    6h 16m
    $107–470
  3. Bus via Santa Ana

    1. Take the bus from Denver Union Station to Las Vegas BusTerminalbus bus
    2. Take the bus from Las Vegas BusTerminal to Santa Ana Bus Stopbus bus
    3. Take the bus from Santa Ana Bus Stop to San Diegobus bus
    24h 45m
    $264–372
  4. Bus, train

    1. Take the bus from Denver to Las Vegas Transportation Centerbus bus
    2. Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    29h 38m
    $423–811
  5. Drive 1,078.6 mi

    1. Drive from Denver to San Diegocar car 1,078.6 mi
    16h 53m
    $197–285
  6. Bus

    1. Take the bus from Denver Union Station to Las Vegas BusTerminalbus bus Greyhound US1200
    2. Take the bus from Las Vegas Strip to San Diegobus bus FlixBus 2037
    27h 1m
    $238–346

Denver to San Diego by bus

Calendar7Weekly Buses
Duration24h 45mAverage Duration
Ticket$264Cheapest Price
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Questions & Answers

What companies run services between Denver, CO, USA and San Diego, CA, USA?

Frontier Airlines, United Airlines, and two other airlines fly from Denver (DEN) to San Diego International Airport (SAN) hourly. Alternatively, you can take a bus from Denver Union Station to San Diego via Las Vegas BusTerminal and Santa Ana Bus Stop in around 24h 45m.

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Train operators
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