There are 7 ways to get from Denver to San Diego by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Denver
best- Fly from Denver (DEN) to San Diego International Airport (SAN)plane DEN - SAN
4h$130–220Bus to Colorado Springs Airport, fly
cheapest- Take the bus from Denver, CO to Colorado Springs, CObus
- Fly from Colorado Springs Airport (COS) to San Diego International Airport (SAN)plane COS - SAN
6h 21m$92–420Bus via Santa Ana
- Take the bus from Denver Union Station to Las Vegas Bus Terminalbus
- Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus
- Take the bus from Santa Ana Bus Stop to San Diegobus
24h 45m$172–278Bus, train
- Take the bus from Denver to Las Vegas Transportation Centerbus
- Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diegotrain
29h 38m$359–751Drive 1,078.6 mi
- Drive from Denver to San Diegocar 1,078.6 mi
16h 54m$197–285Bus (Greyhound)
- Take the bus from Denver Union Station to Las Vegas Bus Terminalbus Greyhound US1200
- Take the bus from Las Vegas Bus Terminal to San Diego Greyhound Bus Stopbus Greyhound US0901
24h 58m$174–282Bus via Las Cruces
- Take the bus from Denver to Las Crucesbus Lxus 1121 / ...
- Take the bus from Las Cruces, NM to Cross Border Express, San Diegobus El Paso
34h 14m$228–364
Denver to San Diego by bus
Comparing Your Travel Options
The cheapest way to get from Denver to San Diego is to fly which costs $130 - $220 and takes 4h.
The fastest way to get from Denver to San Diego is to fly which takes 4h and costs $130 - $220.
No, there is no direct bus from Denver station to San Diego. However, there are services departing from Denver Union Station and arriving at San Diego via Las Vegas Bus Terminal and Santa Ana Bus Stop. The journey, including transfers, takes approximately 24h 45m.
The distance between Denver and San Diego is 880 miles. The road distance is 1084.9 miles.
The best way to get from Denver to San Diego without a car is to bus via Santa Ana which takes 24h 45m and costs $170 - $280.
It takes approximately 4h to get from Denver to San Diego, including transfers.
Denver to San Diego bus services, operated by Greyhound USA, depart from Denver Union Station.
The best way to get from Denver to San Diego is to fly which takes 4h and costs $130 - $220. Alternatively, you can bus via Santa Ana, which costs $170 - $280 and takes 24h 45m.
Denver to San Diego bus services, operated by Greyhound USA, arrive at Las Vegas Bus Terminal station.
San Diego is 1h behind Denver. It is currently 4:03 PM in Denver and 3:03 PM in San Diego.
What companies run services between Denver, CO, USA and San Diego, CA, USA?
Frontier Airlines, United Airlines, and two other airlines fly from Denver (DEN) to San Diego International Airport (SAN) hourly. Alternatively, you can take a bus from Denver Union Station to San Diego via Las Vegas Bus Terminal and Santa Ana Bus Stop in around 24h 45m.
- Website
- southwest.com
Flights from Denver to San Diego International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- $75–390
Flights from Colorado Springs Airport to San Diego International Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $75–400
Flights from Colorado Springs Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 4h 15m
- When
- Monday to Saturday
- Estimated price
- $80–410
Flights from Colorado Springs Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 4h 13m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $80–410
Flights from Colorado Springs Airport to San Diego International Airport via Denver
- Ave. Duration
- 4h 20m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $85–420
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Las Vegas Amtrak Station to Fullerton Amtrak Station
- Ave. Duration
- 20h 32m
- Frequency
- Once daily
- Estimated price
- $260–600
- Website
- Amtrak
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- $26–60
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Denver Union Station to Las Vegas Bus Terminal
- Ave. Duration
- 15h 30m
- Frequency
- Once daily
- Estimated price
- $110–190
- Website
- Greyhound
Bus from Las Vegas Bus Terminal to Santa Ana Bus Stop
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Denver Union Station to Las Vegas Bus Terminal
- Ave. Duration
- 15h 30m
- Frequency
- Once daily
- Estimated price
- $110–190
- Website
- Greyhound
Bus from Las Vegas Bus Terminal to San Diego Greyhound Bus Stop
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $55–95
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Denver to San Diego is 1085 miles. It takes approximately 16h 54m to drive from Denver to San Diego.
Book your Denver to San Diego bus tickets online with Omio and FlixBus.
There are 2370+ hotels available in San Diego.








