There are 5 ways to get from Denver to Sanibel Island by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Denver (DEN) to Ft. Myers (RSW)plane DEN - RSW
5h 40m$232–577Bus via Fort Worth
- Take the bus from Denver Union Station to Fort Worth Downtownbus
- Take the bus from Ft Worth Bus Station to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
45h 14m$407–566Train, bus
- Take the train from Denver to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Tampatrain
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
2d 17h$1,598–2,576Drive 1,914 mi
- Drive from Denver to Sanibel Islandcar 1,914 mi
33h 36m$350–505Bus
- Take the bus from Denver Union Station to Ft Worth Bus Stationbus
- Take the bus from Ft Worth Bus Station to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
2d$430–601
Denver (DEN) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from Denver to Sanibel Island is to fly which costs $230 - $600 and takes 5h 40m.
The fastest way to get from Denver to Sanibel Island is to fly which takes 5h 40m and costs $230 - $600.
No, there is no direct bus from Denver station to Sanibel Island. However, there are services departing from Denver Union Station and arriving at Fort Myers via Ft Worth Bus Station and Houston - Harrisburg Blvd. The journey, including transfers, takes approximately 45h 14m.
The distance between Denver and Sanibel Island is 1662 miles. The road distance is 1925.2 miles.
The best way to get from Denver to Sanibel Island without a car is to bus via Fort Worth which takes 45h 14m and costs $400 - $600.
It takes approximately 5h 40m to get from Denver to Sanibel Island, including transfers.
Denver to Sanibel Island bus services, operated by Flixbus USA, depart from Denver Union Station.
The best way to get from Denver to Sanibel Island is to fly which takes 5h 40m and costs $230 - $600. Alternatively, you can bus via Fort Worth, which costs $400 - $600 and takes 45h 14m.
Denver to Sanibel Island bus services, operated by Flixbus USA, arrive at Fort Worth Downtown station.
Yes, the driving distance between Denver to Sanibel Island is 1925 miles. It takes approximately 33h 36m to drive from Denver to Sanibel Island.
What companies run services between Denver, CO, USA and Sanibel Island, FL, USA?
Frontier Airlines, United Airlines, and two other airlines fly from Denver (DEN) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Denver Union Station to Sanibel Island via Fort Worth Downtown, Ft Worth Bus Station, Houston Bus Station, Houston - Harrisburg Blvd, and Fort Myers in around 45h 14m.
- Website
- southwest.com
Flights from Denver to Ft. Myers
- Ave. Duration
- 3h 33m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $150–700
Flights from Denver to Ft. Myers via St. Louis
- Ave. Duration
- 5h 27m
- When
- Monday, Sunday, Tuesday, and Wednesday
- Estimated price
- $160–700
Flights from Denver to Ft. Myers via Orlando
- Ave. Duration
- 5h 25m
- When
- Tuesday to Friday
- Estimated price
- $150–700
Flights from Denver to Ft. Myers via Nashville
- Ave. Duration
- 5h 21m
- When
- Monday to Wednesday
- Estimated price
- $160–700
- Website
- united.com
Flights from Denver to Ft. Myers
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $150–700
- Website
- flyfrontier.com
Flights from Denver to Ft. Myers
- Ave. Duration
- 3h 39m
- When
- Friday
- Estimated price
- $160–500
- Website
- delta.com
Flights from Denver to Ft. Myers via Atlanta
- Ave. Duration
- 5h 44m
- When
- Saturday
- Estimated price
- $150–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Denver to Chicago Union Station
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Chicago Union Station to Tampa
- Ave. Duration
- 40h 47m
- Frequency
- Once daily
- Estimated price
- $950–1,600
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Denver Union Station to Fort Worth Downtown
- Ave. Duration
- 16h 30m
- Frequency
- 6 times a week
- Estimated price
- $130–210
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Ft Worth Bus Station to Houston Bus Station
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Denver Union Station to Ft Worth Bus Station
- Ave. Duration
- 19h 25m
- Frequency
- Once daily
- Estimated price
- $160–240
- Website
- Greyhound
Bus from Ft Worth Bus Station to Houston Bus Station
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Fort Myers
- Ave. Duration
- 20h 38m
- Frequency
- Once daily
- Estimated price
- $170–220
- Schedules at
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Fort Myers
- Ave. Duration
- 20h 38m
- Frequency
- Once daily
- Estimated price
- $170–220
- Schedules at
- Omnibus Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 4325+ hotels available in Sanibel Island.











