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How to get fromDenver to Santeeby plane, car, bus (Greyhound, Flixbus), train, or bus

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There are 7 ways to get from Denver to Santee by plane, car, bus (Greyhound, Flixbus), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport, drive

    best
    1. Fly from Denver (DEN) to Charleston International Airport (CHS)plane plane DEN - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    6h 4m
    $370–826

  2. Drive 1,630.5 mi

    cheapest
    1. Drive from Denver to Santeecar car 1,630.5 mi
    27h 15m
    $298–430

  3. Bus

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Orangeburgbus bus
    36h 2m
    $410–616

  4. Train, bus

    1. Take the train from Denver to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Savannah Stationtrain train
    3. Take the bus from Savannah to Orangeburgbus bus
    2d 6h
    $886–1,757

  5. Fly to Columbia, drive

    1. Fly from Denver (DEN) to Columbia (CAE)plane plane DEN - CAE
    2. Drive from Columbia-Airport-CAE to Santeecar car
    7h 36m
    $320–1,326

  6. Fly to Savannah, bus

    1. Fly from Denver (DEN) to Savannah (SAV)plane plane DEN - SAV
    2. Take the bus from Savannah to Orangeburgbus bus
    8h 27m
    $305–930

  7. Bus via Champaign

    1. Take the bus from Denver to Champaignbus bus
    2. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Orangeburgbus bus
    42h 27m
    $519–722

Denver (DEN) to Charleston International Airport (CHS) flights

Calendar68Weekly Planes
Duration4h 53mAverage Duration
Ticket$139Cheapest Price
See schedules

Questions & Answers

Map of how to get from Denver to Santee.ExpandLaunch map view
  • Distance: 1,529.8 mi
  • Duration: 6h 4m

What companies run services between Denver, CO, USA and Santee, SC, USA?

You can take a bus from Denver Union Station to Santee via St Louis Bus Station, Atlanta, and Orangeburg in around 36h 2m.

Airlines
Train operators
Bus operators

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