There are 7 ways to get from Depew to Brooklyn by plane, subway, train (Amtrak), bus (Flixbus), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Laguardia Airport, subway
best- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane BUF - LGA
- Take the subway from Jackson Hts-Roosevelt Av to 15 St-Prospect Parksubway
2h 42m$90–503Drive 352.6 mi
cheapest- Drive from Depew to Brooklyncar 352.6 mi
7h 17m$65–93Train via Ny Moynihan Train Hall At Penn Station (Amtrak)
- Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
9h 47m$235–375Bus (Flixbus)
- Take the bus from Buffalo to New York Midtownbus FlixBus 2686 / ...
10h 59m$70–105Fly to John F. Kennedy International Airport
- Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane BUF - JFK
2h 8m$69–306Fly to Newark Liberty International Airport, line 2 subway
- Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane BUF - EWR
- Take the subway from 34 St-Penn Station to Church Avsubway
3h 11m$82–332Train
- Take the train from Buffalo to New York Penn Stationtrain VIA Rail
10h 33m$115–285
Depew to Brooklyn by bus, train, and subway (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Depew to Brooklyn is to drive which costs $60 - $95 and takes 7h 17m.
The fastest way to get from Depew to Brooklyn is to fly which takes 2h 8m and costs $65 - $310.
No, there is no direct bus from Depew to Brooklyn. However, there are services departing from Broadway & Meridian Street and arriving at New York Midtown via Buffalo. The journey, including transfers, takes approximately 10h 59m.
No, there is no direct train from Depew station to Brooklyn. However, there are services departing from Buffalo Depew Station and arriving at Church Av via 34 St-Penn Station. The journey, including transfers, takes approximately 9h 47m.
The distance between Depew and Brooklyn is 314 miles. The road distance is 354.6 miles.
The best way to get from Depew to Brooklyn without a car is to train via Ny Moynihan Train Hall At Penn Station which takes 9h 47m and costs $230 - $380.
It takes approximately 2h 42m to get from Depew to Brooklyn, including transfers.
Depew to Brooklyn bus services, operated by Flixbus USA, depart from Buffalo station.
Depew to Brooklyn train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Depew to Brooklyn is to train via Ny Moynihan Train Hall At Penn Station which takes 9h 47m and costs $230 - $380. Alternatively, you can bus, which costs $70 - $110 and takes 10h 59m, you could also fly, which costs $65 - $310 and takes 2h 8m.
What companies run services between Depew, NY, USA and Brooklyn, Kings County, NY, USA?
Amtrak operates a train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station 4 times a day. Tickets cost $230–370 and the journey takes 8h. Alternatively, Flixbus USA operates a bus from Buffalo to New York Midtown every 4 hours. Tickets cost $65–100 and the journey takes 8h 25m.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $70–480
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–270
- Website
- united.com
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $40–280
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport via Washington Dulles
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $50–320
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $70–480
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $40–270
- Phone
- 877-690-5116
- Website
- MTA Homepage
Subway from Jackson Hts-Roosevelt Av to 15 St-Prospect Park
- Ave. Duration
- 47 min
- Frequency
- Every 10 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
Subway from 34 St-Penn Station to Church Av
- Ave. Duration
- 37 min
- Frequency
- Every 10 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h
- Frequency
- 4 times a day
- Estimated price
- $230–370
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo to New York Penn Station
- Ave. Duration
- 8h 46m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- VIA Rail
- Escape
- $110–260
- Business
- $150–270
- Business Plus
- $160–280
- Economy
- $120–260
- Economy Plus
- $140–270
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to New York Midtown
- Ave. Duration
- 8h 25m
- Frequency
- Every 4 hours
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Depew to Brooklyn bus services, operated by Flixbus USA, arrive at New York Midtown station.
Depew to Brooklyn train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Depew to Brooklyn is 355 miles. It takes approximately 7h 17m to drive from Depew to Brooklyn.
There are 3590+ hotels available in Brooklyn.
















