There are 4 ways to get from Depew to Charleston by plane, train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Buffalo Niagara International Airport (BUF) to Charleston International Airport (CHS)plane BUF - CHS
3h 56m$109–512Train (Amtrak)
- Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain Silver Meteor / ...
26h 11m$636–1,026Drive 863.9 mi
- Drive from Depew to Charlestoncar 863.9 mi
14h 47m$153–221Bus, train
- Take the bus from Buffalo to Newark Penn Stationbus FlixBus N2686 / ...
- Take the train from Newark Penn Station to Charleston Amtrak Stationtrain Silver Meteor / ...
26h 31m$461–766
Depew to Charleston by bus and train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Depew to Charleston is to drive which costs $150 - $230 and takes 14h 47m.
The fastest way to get from Depew to Charleston is to fly which takes 3h 56m and costs $100 - $550.
No, there is no direct train from Depew station to Charleston station. However, there are services departing from Buffalo Depew Station and arriving at Charleston Amtrak Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 26h 11m.
The distance between Depew and Charleston is 721 miles. The road distance is 869 miles.
The best way to get from Depew to Charleston without a car is to train which takes 26h 11m and costs $600 - $1,100.
It takes approximately 3h 56m to get from Depew to Charleston, including transfers.
Depew to Charleston train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Depew to Charleston is to fly which takes 3h 56m and costs $100 - $550. Alternatively, you can train, which costs $600 - $1,100 and takes 26h 11m.
Depew to Charleston train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Depew to Charleston is 869 miles. It takes approximately 14h 47m to drive from Depew to Charleston.
What companies run services between Depew, NY, USA and Charleston, SC, USA?
Breeze Airways, American Airlines, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Charleston International Airport (CHS) every 4 hours. Alternatively, you can take a bus from Broadway & Meridian Street to Transit Mall via Dick Road & AMTRAK Station, Buffalo Depew Station, Ny Moynihan Train Hall At Penn Station, Charleston Amtrak Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 26h 11m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Charleston International Airport via Baltimore
- Ave. Duration
- 4h 40m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–500
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $90–490
Flights from Buffalo Niagara International Airport to Charleston International Airport via Philadelphia
- Ave. Duration
- 5h 16m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–550
Flights from Buffalo Niagara International Airport to Charleston International Airport via Reagan Washington
- Ave. Duration
- 5h 21m
- When
- Monday to Friday
- Estimated price
- $90–490
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $110–550
- Website
- flybreeze.com
Flights from Buffalo Niagara International Airport to Charleston International Airport
- Ave. Duration
- 2h 15m
- When
- Monday and Friday
- Estimated price
- $180–1,100
- Website
- united.com
Flights from Buffalo Niagara International Airport to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 16m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h
- Frequency
- 4 times a day
- Estimated price
- $230–370
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Station
- Ave. Duration
- 14h 18m
- Frequency
- Twice daily
- Estimated price
- $400–650
- Website
- Amtrak
Train from Newark Penn Station to Charleston Amtrak Station
- Ave. Duration
- 13h 55m
- Frequency
- Twice daily
- Estimated price
- $390–650
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to Newark Penn Station
- Ave. Duration
- 7h 50m
- Frequency
- 5 times a day
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Newark Penn Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- Greyhound
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Booking & Getting There
There are 1905+ hotels available in Charleston.