Rome2Rio

How to get fromDepew to Las Vegasby plane, train, bus, bus (Greyhound), or car

Find Transport to Las Vegas

See all options

There are 5 ways to get from Depew to Las Vegas by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Harry Reid International Airport (LAS)plane plane BUF - LAS
    5h 4m
    $241–924

  2. Train, bus (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Kingman Stationtrain train
    3. Take the bus from Kingman Station to South Strip Transit Terminalbus bus
    2d 3h
    $812–1,717

  3. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Las Vegas BusTerminalbus bus
    2d 5h
    $406–761

  4. Drive 2,265.4 mi

    1. Drive from Depew to Las Vegascar car 2,265.4 mi
    36h
    $414–598

  5. Bus via Reading

    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus
    2. Take the bus from Greyhound Station Cincinnati to Indianapolis, INbus bus
    3. Take the bus from Indianapolis to Denverbus bus
    4. Take the bus from Denver Union Station to Las Vegas BusTerminalbus bus
    2d 11h
    $464–796

Depew to Las Vegas by bus and train (Amtrak)

Calendar1Weekly Services
Duration2d 3hAverage Duration
Ticket$812Cheapest Price
See schedules

Questions & Answers

Map of how to get from Depew to Las Vegas.ExpandLaunch map view
  • Distance: 1,988.7 mi
  • Duration: 5h 4m

What companies run services between Depew, NY, USA and Las Vegas, NV, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Harry Reid International Airport (LAS) every 4 hours. Alternatively, you can take a bus from Broadway & Meridian Street to South Strip Transit Terminal via Buffalo, Cleveland Bus Station, Chicago Bus Station, Denver Union Station, Las Vegas BusTerminal, and SSTT Exit in around 2d 5h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers