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How to get fromDepew to Las Vegasby plane, train, bus, bus (Greyhound, Flixbus), or car

Find Transport to Las Vegas

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There are 4 ways to get from Depew to Las Vegas by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Harry Reid International Airport (LAS)plane plane BUF - LAS
    5h 13m
    $161–624

  2. Train, bus (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Kingman Stationtrain train
    3. Take the bus from Kingman Station to South Strip Transit Terminalbus bus
    2d 3h

  3. Bus

    1. Take the bus from Buffalo to Columbusbus bus
    2. Take the bus from Columbus to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Phoenix Bus Stationbus bus
    4. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Las Vegas Downtownbus bus
    2d 9h
    $412–662

  4. Drive  2,265.4 mi

    1. Drive from Depew to Las Vegascar car 2,265.4 mi
    36h
    $414–598

Buffalo Niagara International Airport (BUF) to Harry Reid International Airport (LAS) flights

Calendar43Weekly Planes
Duration6h 22mAverage Duration
Ticket$144Cheapest Price
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Comparing Your Travel Options

Map of how to get from Depew to Las Vegas.ExpandLaunch map view
  • Distance: 1,989.3 mi
  • Duration: 5h 13m

What companies run services between Depew, NY, USA and Las Vegas, NV, USA?

Southwest Airlines, Delta, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Harry Reid International Airport (LAS) every 4 hours. Alternatively, you can take a bus from Broadway & Meridian Street to Las Vegas Downtown via Buffalo, Columbus, St Louis Bus Station, Phoenix, Bus Station (E Buckeye Rd), 24th St Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and Phoenix Sky Harbor Airport/44th Street Sky Train Station in around 2d 9h.

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Want to know more about travelling around United States

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