There are 7 ways to get from Depew to New York Penn Station by plane, train, bus (Greyhound), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Laguardia Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane BUF - LGA
2h 10m$105–626Bus via Port Authority Bus Terminal
cheapest- Take the bus from Buffalo to Port Authority Bus Terminalbus Greyhound US0205 / ...
10h 12m$57–252Train
- Take the train from Buffalo to New York Penn Stationtrain VIA Rail
9h 51m$112–292Drive 349.1 mi
- Drive from Depew to New York Penn Stationcar 349.1 mi
7h 5m$64–92Fly to John F. Kennedy International Airport
- Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane BUF - JFK
2h 9m$81–379Fly to Newark Liberty International Airport, train
- Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane BUF - EWR
- Take the train from Newark Airport Railroad Station to New York Penn Stationtrain
2h 21m$87–378Bus (Flixbus)
- Take the bus from Buffalo to New York Midtownbus FlixBus N2686 / ...
10h 24m$72–132
Depew to New York Penn Station by bus and train
Questions & Answers
The cheapest way to get from Depew to New York Penn Station is to drive which costs $60 - $95 and takes 7h 5m.
The fastest way to get from Depew to New York Penn Station is to fly which takes 2h 9m and costs $80 - $380.
No, there is no direct bus from Depew to New York Penn Station. However, there are services departing from Broadway & Meridian Street and arriving at Port Authority Bus Terminal via Buffalo. The journey, including transfers, takes approximately 10h 12m.
No, there is no direct train from Depew to New York Penn Station station. However, there are services departing from Buffalo and arriving at New York Penn Station via . The journey, including transfers, takes approximately 9h 51m.
The distance between Depew and New York Penn Station is 306 miles. The road distance is 351.1 miles.
The best way to get from Depew to New York Penn Station without a car is to train which takes 9h 51m and costs $110 - $300.
It takes approximately 2h 10m to get from Depew to New York Penn Station, including transfers.
Depew to New York Penn Station bus services, operated by Greyhound USA, depart from Buffalo station.
Depew to New York Penn Station train services, operated by VIA Rail, depart from Buffalo station.
The best way to get from Depew to New York Penn Station is to fly which takes 2h 10m and costs $100 - $650. Alternatively, you can train, which costs $110 - $300 and takes 9h 51m, you could also bus via Port Authority Bus Terminal, which costs $55 - $260 and takes 10h 12m.
What companies run services between Depew, NY, USA and New York Penn Station, NY, USA?
American Airlines, Delta, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA) every 4 hours. Alternatively, VIA Rail operates a train from Buffalo to New York Penn Station once daily. Tickets cost $110–290 and the journey takes 8h 46m.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $85–600
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $50–340
- Website
- united.com
Flights from Buffalo Niagara International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- $110–650
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $50–330
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport via Washington Dulles
- Ave. Duration
- 3h 47m
- When
- Saturday
- Estimated price
- $65–380
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $50–340
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport via Boston
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $70–400
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $85–600
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo to New York Penn Station
- Ave. Duration
- 8h 46m
- Frequency
- Once daily
- Estimated price
- $110–290
- Website
- VIA Rail
- Escape
- $110–260
- Business
- $150–280
- Business Plus
- $160–290
- Economy
- $130–270
- Economy Plus
- $140–270
- Phone
- +1 973-275-5555
- Website
- New Jersey Transit
Train from Newark Airport Railroad Station to New York Penn Station
- Ave. Duration
- 27 min
- Frequency
- Every 20 minutes
- Estimated price
- $15–19
- Website
- New Jersey Transit
- Website
- NJ Transit: World Cup 2026
- Adult Airport
- $15–19
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 5m
- Frequency
- Every 3 hours
- Estimated price
- $60–120
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–250
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $55–240
- Flexible
- $100–250
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to New York Midtown
- Ave. Duration
- 8h 35m
- Frequency
- Hourly
- Estimated price
- $70–130
- Schedules at
- Flixbus USA
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More Questions & Answers
Depew to New York Penn Station bus services, operated by Greyhound USA, arrive at Port Authority Bus Terminal station.
Depew to New York Penn Station train services, operated by VIA Rail, arrive at New York Penn Station.
Yes, the driving distance between Depew to New York Penn Station is 351 miles. It takes approximately 7h 5m to drive from Depew to New York Penn Station.
There are 2970+ hotels available in New York Penn Station.