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How to get fromDepew to Pittsburghby plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Find Transport to Pittsburgh

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There are 5 ways to get from Depew to Pittsburgh by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Pittsburgh International Airport (PIT)plane plane BUF - PIT
    4h 53m
    $92–480

  2. Bus via Erie

    cheapest
    1. Take the bus from Buffalo to Eriebus bus FlixBus 2526
    2. Take the bus from Erie to Pittsburgh Intermodal Stationbus bus Greyhound US0440s
    8h 14m
    $40–66

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    8h 31m
    $177–282

  4. Drive  219.4 mi

    1. Drive from Depew to Pittsburghcar car 219.4 mi
    3h 50m
    $40–58

  5. Bus

    1. Take the bus from Buffalo to Pittsburghbus bus Fab530
    9h 29m
    $72–242

Depew to Pittsburgh by bus

Calendar7Weekly Buses
Duration8h 14mAverage Duration
Ticket$40Cheapest Price
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Comparing Your Travel Options

Map of how to get from Depew to Pittsburgh.ExpandLaunch map view
  • Distance: 215.7 mi
  • Duration: 4h 53m

What companies run services between Depew, NY, USA and Pittsburgh, PA, USA?

Delta, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Pittsburgh International Airport (PIT) hourly. Alternatively, you can take a bus from Broadway & Meridian Street to Pittsburgh Intermodal Station via Buffalo and Erie in around 8h 14m.

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