There are 5 ways to get from Depew to Syracuse by train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Buffalo Depew Station to Syracuse Regional Transportation Centertrain Empire Service / ...
3h 15m$37–192Drive 138.5 mi
cheapest- Drive from Depew to Syracusecar 138.5 mi
2h 34m$26–37Line 2 bus, bus
- Take the bus from Broadway & Meridian Street to Ellicott Street & MTC Staticbus 2
- Take the bus from Buffalo to Syracuse Bus Stationbus Greyhound US0215 / ...
3h 49m$29–92Fly
- Fly from Buffalo Niagara International Airport (BUF) to Syracuse Hancock International Airport (SYR)plane BUF - SYR
5h 35m$168–878Line 2 bus, bus via Buffalo Niagara International Airport
- Take the bus from Broadway & Meridian Street to Ellicott Street & MTC Staticbus 2
- Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus FlixBus 2686 / ...
5h 21m$34–120
Depew to Syracuse by bus and train
Questions & Answers
The cheapest way to get from Depew to Syracuse is to drive which costs $25 - $40 and takes 2h 34m.
The fastest way to get from Depew to Syracuse is to drive which takes 2h 34m and costs $25 - $40.
No, there is no direct bus from Depew to Syracuse station. However, there are services departing from Broadway & Meridian Street and arriving at Syracuse Bus Station via Buffalo. The journey, including transfers, takes approximately 3h 49m.
No, there is no direct train from Depew station to Syracuse. However, there are services departing from Buffalo Depew Station and arriving at Syracuse Regional Transportation Center via . The journey, including transfers, takes approximately 3h 15m.
The distance between Depew and Syracuse is 143 miles. The road distance is 139.3 miles.
The best way to get from Depew to Syracuse without a car is to train which takes 3h 15m and costs $35 - $200.
It takes approximately 3h 15m to get from Depew to Syracuse, including transfers.
Depew to Syracuse bus services, operated by NFTA, depart from Broadway & Meridian Street station.
Depew to Syracuse train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Depew to Syracuse is to train which takes 3h 15m and costs $35 - $200. Alternatively, you can line 2 bus and bus, which costs $29 - $95 and takes 3h 49m, you could also fly, which costs $160 - $900 and takes 5h 35m.
What companies run services between Depew, NY, USA and Syracuse, NY, USA?
Amtrak operates a train from Buffalo Depew Station to Syracuse Regional Transportation Center 5 times a day. Tickets cost $40–95 and the journey takes 2h 10m. VIA Rail also services this route once daily. Alternatively, you can take a bus from Broadway & Meridian Street to Syracuse Bus Station via Buffalo in around 3h 49m.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $170–950
Flights from Buffalo Niagara International Airport to Syracuse Hancock International Airport via New York JFK
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $150–900
Flights from Buffalo Niagara International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $150–850
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Syracuse Hancock International Airport via Philadelphia
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $150–850
Flights from Buffalo Niagara International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $160–900
- Website
- united.com
Flights from Buffalo Niagara International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $160–900
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Syracuse Hancock International Airport via New York JFK
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $150–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a day
- Estimated price
- $40–95
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo Depew Station to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $35–190
- Website
- VIA Rail
- Escape
- $35–110
- Business
- $70–180
- Business Plus
- $80–190
- Economy
- $40–110
- Economy Plus
- $45–120
- Phone
- +1 716-855-7211
- [email protected]
- Website
- NFTA
Bus from Broadway & Meridian Street to Ellicott Street & MTC Static
- Ave. Duration
- 59 min
- Frequency
- Every 4 hours
- Estimated price
- $2
- Website
- NFTA
Bus from Broadway & Meridian Street to Ellicott Street & MTC Static
- Ave. Duration
- 59 min
- Frequency
- Every 4 hours
- Estimated price
- $2
- Website
- NFTA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Every 3 hours
- Estimated price
- $22–45
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Every 2 hours
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 2 hours
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
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More Questions & Answers
Depew to Syracuse bus services, operated by NFTA, arrive at Ellicott Street & MTC Static station.
Depew to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Yes, the driving distance between Depew to Syracuse is 139 miles. It takes approximately 2h 34m to drive from Depew to Syracuse.
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