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How to get fromDes Moines Airport (DSM) to Myrtle Beachby plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, bus (Greyhound, Flixbus), or shuttle

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There are 7 ways to get from Des Moines Airport (DSM) to Myrtle Beach by plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, bus (Greyhound, Flixbus), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Myrtle Beach

    best
    1. Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane plane DSM - MYR
    4h 23m
    $135–595

  2. Bus via Carbondale

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    31h 34m
    $260–606

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    45h 38m
    $517–1,188

  4. Drive 1,176.2 mi

    1. Drive from Des Moines Airport (DSM) to Myrtle Beachcar car 1,176.2 mi
    21h 58m
    $215–311

  5. Fly to Wilmington International Airport, bus

    1. Fly from Des Moines (DSM) to Wilmington International Airport (ILM)plane plane DSM - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    7h 18m
    $179–757

  6. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    32h 19m
    $260–601

  7. Shuttle, bus

    1. Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State Universityshuttle bus
    2. Take the bus from Ames to Kansas Citybus bus
    3. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    33h 45m
    $312–620

Des Moines (DSM) to Myrtle Beach (MYR) flights

Calendar45Weekly Planes
Duration5h 39mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Des Moines Airport (DSM) to Myrtle Beach.ExpandLaunch map view
  • Distance: 972.2 mi
  • Duration: 4h 23m

What companies run services between Des Moines Airport (DSM), USA and Myrtle Beach, SC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a shuttle from Des Moines International Airport, IA to Myrtle Beach Bus Station via Ankeny, IA, Des Moines, St Louis Bus Station, Carbondale Intermodal Station, and Atlanta Bus Station in around 31h 34m.

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