There are 5 ways to get from Des Moines Airport (DSM) to St. Louis by plane, bus (Greyhound), rideshare, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Lambert–St. Louis International Airport
best- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
4h 31m$145–770Drive 330.5 mi
cheapest- Drive from Des Moines Airport (DSM) to St. Louiscar 330.5 mi
6h 52m$61–88Bus (Greyhound)
- Take the bus from Des Moines to St Louis Bus Stationbus Greyhound US0153S
9h 59m$120–331Airport Transfer
- Take the rideshare from Des Moines-DSM to St. Louis330.5 mi
6h 52mFly to Abraham Lincoln Capital Airport, train
- Fly from Des Moines (DSM) to Abraham Lincoln Capital Airport (SPI)plane DSM - SPI
- Take the train from Springfield to St. Louistrain
6h 36m$134–594
Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Des Moines Airport (DSM) to St. Louis is to drive which costs $60 - $90 and takes 6h 52m.
The fastest way to get from Des Moines Airport (DSM) to St. Louis is to fly which takes 4h 31m and costs $140 - $800.
No, there is no direct bus from Des Moines Airport (DSM) to St. Louis station. However, there are services departing from Des Moines and arriving at St Louis Bus Station via . The journey, including transfers, takes approximately 9h 59m.
The distance between Des Moines Airport (DSM) and St. Louis is 275 miles. The road distance is 332.4 miles.
The best way to get from Des Moines Airport (DSM) to St. Louis without a car is to bus which takes 9h 59m and costs $120 - $340.
It takes approximately 4h 31m to get from Des Moines Airport (DSM) to St. Louis, including transfers.
Des Moines Airport (DSM) to St. Louis bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines Airport (DSM) to St. Louis is to fly which takes 4h 31m and costs $140 - $800. Alternatively, you can bus, which costs $120 - $340 and takes 9h 59m.
Des Moines Airport (DSM) to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Des Moines Airport (DSM) to St. Louis is 332 miles. It takes approximately 6h 52m to drive from Des Moines Airport (DSM) to St. Louis.
What companies run services between Des Moines Airport (DSM), USA and St. Louis, MO, USA?
Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Greyhound USA operates a bus from Des Moines to St Louis Bus Station twice daily. Tickets cost $60–120 and the journey takes 8h 20m.
- Website
- aa.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Des Moines to Abraham Lincoln Capital Airport via Chicago O'Hare
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $90–550
- Website
- united.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $260–1,200
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $140–800
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 56m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $260–1,200
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $160–850
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Des Moines to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $200–950
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Springfield to St. Louis
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $30–65
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- Greyhound
- Website
- https://www.mozio.com
Rideshare from Des Moines-DSM to St. Louis
- Ave. Duration
- 6h 52m
- Frequency
- On demand
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More Questions & Answers
There are 467+ hotels available in St. Louis.
Check out Blablacar's carpooling service for rideshare options between Des Moines Airport (DSM) and St. Louis. A great option if you don't have a driver's licence or want to avoid public transport.