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How to get fromDes Moines Airport (DSM) to Tupeloby plane, car, bus (Greyhound, Flixbus), bus, shuttle, or train

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There are 8 ways to get from Des Moines Airport (DSM) to Tupelo by plane, car, bus (Greyhound, Flixbus), bus, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Des Moines (DSM) to Golden Triangle Regional Airport (GTR)plane plane DSM - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    6h 41m
    $155–689

  2. Drive 682.4 mi

    cheapest
    1. Drive from Des Moines Airport (DSM) to Tupelocar car 682.4 mi
    12h 58m
    $125–180

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    19h 18m
    $186–459

  4. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Des Moines (DSM) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane DSM - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    6h 24m
    $183–820

  5. Fly to Tupelo Regional Airport

    1. Fly from Des Moines (DSM) to Tupelo Regional Airport (TUP)plane plane DSM - TUP
    5h 1m
    $126–585

  6. Fly to Memphis, bus

    1. Fly from Des Moines (DSM) to Memphis (MEM)plane plane DSM - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    8h 35m
    $242–1,105

  7. Shuttle, bus

    1. Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State Universityshuttle bus
    2. Take the bus from Ames to Kansas Citybus bus
    3. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    5. Take the bus from Memphis Bus Station to Tupelobus bus
    20h 44m
    $238–478

  8. Bus, train

    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    20h 58m
    $248–600

Des Moines (DSM) to Golden Triangle Regional Airport (GTR) flights

Calendar21Weekly Planes
Duration6h 25mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from Des Moines Airport (DSM) to Tupelo.ExpandLaunch map view
  • Distance: 685.2 mi
  • Duration: 6h 41m

What companies run services between Des Moines Airport (DSM), USA and Tupelo, MS, USA?

You can take a shuttle from Des Moines International Airport, IA to Tupelo via Ankeny, IA, Des Moines, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 19h 18m. Alternatively, American Airlines, Corporate Flight Management Inc, and four other airlines fly from Des Moines (DSM) to Tupelo Regional Airport (TUP) twice daily.

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