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How to get fromDes Moines International Airport to Lexingtonby plane, car, bus, or taxi

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There are 7 ways to get from Des Moines International Airport to Lexington by plane, car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Covington, drive

    best
    1. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    4h 56m
    $147–755

  2. Drive 641.6 mi

    cheapest
    1. Drive from Des Moines International Airport to Lexingtoncar car 641.6 mi
    11h 56m
    $118–170

  3. Bus, drive

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    17h 51m
    $124–236

  4. Fly to Louisville International Airport, drive

    1. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 4m
    $146–748

  5. Fly to Blue Grass Airport

    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    6h 40m
    $200–1,070

  6. Bus, taxi, drive

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Paoli Walmartbus bus
    3. Take the taxi from Paoli Walmart to Indiana University Southeasttaxi taxi
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    19h 2m
    $242–376

  7. Bus, drive via St. Louis

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Corydon, INbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    19h 21m
    $210–343

Des Moines (DSM) to Covington (CVG) flights

Calendar123Weekly Planes
Duration5h 2mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

Map of how to get from Des Moines International Airport to Lexington.ExpandLaunch map view
  • Distance: 585.3 mi
  • Duration: 4h 56m

What companies run services between Des Moines International Airport, IA, USA and Lexington, KY, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Blue Grass Airport (LEX) hourly.

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