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How to get fromDes Moines to Amarilloby plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

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There are 4 ways to get from Des Moines to Amarillo by plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Rick Husband Amarillo International Airport (AMA)plane plane DSM - AMA
    5h 19m
    $127–491

  2. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus
    2. Take the bus from Kansas City Bus Station to Oklahoma City Bus Stationbus bus
    3. Take the bus from Oklahoma City Bus Station to Amarillo Multimodal Transfer Stabus bus
    17h 30m
    $136–228

  3. Drive  751 mi

    1. Drive from Des Moines to Amarillocar car 751 mi
    13h 3m
    $129–186

  4. Bus

    1. Take the bus from Des Moines to Tulsabus bus Jefferson Lines 801
    2. Take the bus from Tulsa Bus Station to Amarillo Multimodal Transfer Stabus bus Greyhound US1210
    18h 25m
    $169–243

Des Moines to Amarillo by bus

Calendar14Weekly Buses
Duration17h 30mAverage Duration
Ticket$136Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Amarillo.ExpandLaunch map view
  • Distance: 632.6 mi
  • Duration: 5h 19m

What companies run services between Des Moines, IA, USA and Amarillo, TX, USA?

American Airlines and United Airlines fly from Des Moines (DSM) to Rick Husband Amarillo International Airport (AMA) every 4 hours. Alternatively, you can take a bus from Des Moines to Amarillo Multimodal Transfer Sta via Kansas City Bus Station and Oklahoma City Bus Station in around 17h 30m.

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