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How to get fromDes Moines to Amherstby plane, bus, train, bus (Greyhound), or car

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There are 5 ways to get from Des Moines to Amherst by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF)plane plane DSM - BUF
    4h 2m
    $221–999

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    20h 27m
    $100–236

  3. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    19h 59m
    $268–551

  4. Drive 852.2 mi

    1. Drive from Des Moines to Amherstcar car 852.2 mi
    14h 23m
    $156–225

  5. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    22h 1m
    $216–450

Des Moines to Amherst by bus

Calendar7Weekly Buses
Duration20h 27mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Amherst.ExpandLaunch map view
  • Distance: 781.4 mi
  • Duration: 4h 2m

What companies run services between Des Moines, IA, USA and Amherst, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF) every 2 hours. Alternatively, you can take a bus from Des Moines to Main Street & University Station via Chicago, Cleveland, OH, Buffalo, NY, and North Division Street & Ellicott Street in around 20h 27m.

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