Rome2Rio

How to get fromDes Moines to Biloxiby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Find Transport to Biloxi

See all options

There are 6 ways to get from Des Moines to Biloxi by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT)plane plane DSM - GPT
    5h 27m
    $203–816

  2. Fly to Hattiesburg–Laurel Regional Airport, drive

    cheapest
    1. Fly from Des Moines (DSM) to Hattiesburg–Laurel Regional Airport (PIB)plane plane DSM - PIB
    2. Drive from Hattiesburg–Laurel Regional Airport (PIB) to Biloxicar car
    9h 36m
    $163–694

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Texarkanabus bus
    3. Take the bus from Texarkana to Shreveport Bus Stationbus bus
    4. Take the bus from Shreveport Bus Station to Baton Rouge Bus Stationbus bus
    5. Take the bus from Baton Rouge Bus Station to Biloxi Transit Centerbus bus
    25h 45m
    $231–372

  4. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    27h 40m
    $280–621

  5. Drive  964.5 mi

    1. Drive from Des Moines to Biloxicar car 964.5 mi
    17h 13m
    $176–255

  6. Bus via Indianapolis (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to Biloxi Transit Centerbus bus
    29h 30m
    $180–353

Des Moines to Biloxi by bus

Calendar6Weekly Buses
Duration25h 45mAverage Duration
Ticket$231Cheapest Price
See schedules

Questions & Answers

Map of how to get from Des Moines to Biloxi.ExpandLaunch map view
  • Distance: 829.9 mi
  • Duration: 5h 27m

What companies run services between Des Moines, IA, USA and Biloxi, MS, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours. Alternatively, you can take a bus from Des Moines to Biloxi Transit Center via Kansas City, Texarkana, Shreveport Bus Station, and Baton Rouge Bus Station in around 25h 45m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers