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How to get fromDes Moines to Biloxiby plane, bus, train, or car

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There are 5 ways to get from Des Moines to Biloxi by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT)plane plane DSM - GPT
    5h 19m
    $233–916

  2. Drive 964.5 mi

    cheapest
    1. Drive from Des Moines to Biloxicar car 964.5 mi
    17h 13m
    $176–255

  3. Bus, train via Champaign

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    27h 40m
    $340–707

  4. Bus, train

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    28h 33m
    $202–399

  5. Fly to Hattiesburg–Laurel Regional Airport, drive

    1. Fly from Des Moines (DSM) to Hattiesburg–Laurel Regional Airport (PIB)plane plane DSM - PIB
    2. Drive from Hattiesburg–Laurel Regional Airport (PIB) to Biloxicar car
    9h 33m
    $203–794

Des Moines to Biloxi by bus and train

Calendar7Weekly Services
Duration27h 40mAverage Duration
Ticket$340Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Biloxi.ExpandLaunch map view
  • Distance: 829.9 mi
  • Duration: 5h 19m

What companies run services between Des Moines, IA, USA and Biloxi, MS, USA?

Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours.

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