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How to get fromDes Moines to Burlingtonby plane, bus, train, car, taxi, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Des Moines to Burlington by plane, bus, train, car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Mitchell International Airport

    best
    1. Fly from Des Moines (DSM) to General Mitchell International Airport (MKE)plane plane DSM - MKE
    5h 7m
    $193–803

  2. Drive 320.1 mi

    cheapest
    1. Drive from Des Moines to Burlingtoncar car 320.1 mi
    6h 15m
    $59–85

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Fox Laketrain train Md-N
    10h 23m
    $116–177

  4. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the bus from Multi-Modal/Rental Car Facility to Kenosha Brat Stopbus bus
    4h 18m
    $158–553

  5. Fly to Chicago Midway International Airport, train, taxi

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the train from Chicago Union Station to Sturtevant Amtrak Stationtrain train
    3. Take the taxi from Sturtevant Amtrak Station to Burlingtontaxi taxi
    4h 53m
    $167–594

  6. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Sturtevant Amtrak Stationtrain train
    10h 54m
    $155–283

  7. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Mitchell Airportbus bus
    3. Take the bus from Milwaukee, WI - Airport to East Troy Airport Park and Ridebus bus
    11h 57m
    $106–170

Des Moines (DSM) to General Mitchell International Airport (MKE) flights

Calendar137Weekly Planes
Duration5h 10mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Burlington.ExpandLaunch map view
  • Distance: 353.1 mi
  • Duration: 5h 7m

What companies run services between Des Moines, IA, USA and Burlington, WI, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a bus from Des Moines to Burlington via Chicago Bus Station, Milwaukee, WI - Airport, and East Troy Airport Park and Ride in around 11h 57m.

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