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How to get fromDes Moines to Cancúnby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Des Moines to Cancún by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cancún International Airport

    best
    1. Fly from Des Moines (DSM) to Cancún International Airport (CUN)plane plane DSM - CUN
    6h 50m
    $3,340–13,480

  2. Bus

    1. Take the bus from Des Moines to Omahabus bus
    2. Take the bus from Omaha to Monclovabus bus
    3. Take the bus from Monclova to Monterreybus bus
    4. Take the bus from Monterrey to Cárdenasbus bus
    5. Take the bus from Cárdenas to Cancúnbus bus
    2d 18h

  3. Bus, train via Palenque

    1. Take the bus from Des Moines to Bloomingtonbus bus
    2. Take the train from Bloomington-Normal to San Marcos Amtraktrain train
    3. Take the bus from San Marcos to Monterreybus bus
    4. Take the bus from Monterrey to Cárdenasbus bus
    5. Take the bus from Cárdenas to Catazajábus bus
    6. Take the train from Estación Tren Maya Palenque to Estación Tren Maya Cancún Aeropuertotrain train
    3d 5h

  4. Drive 4,119.4 km

    1. Drive from Des Moines to Cancúncar car 4,119.4 km
    47h 51m
    $7,953–11,487

  5. Fly to Tulum International Airport, train

    1. Fly from Des Moines (DSM) to Tulum International Airport (TQO)plane plane DSM - TQO
    2. Take the train from Estación Tren Maya Tulum Aeropuerto to Estación Tren Maya Cancún Aeropuertotrain train
    9h 31m
    $5,745–20,660

  6. Bus via Irving

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to McAllen Central Stationbus bus
    4. Take the bus from Reynosa to Cárdenasbus bus
    5. Take the bus from Cárdenas to Cancúnbus bus
    2d 23h
    $7,777–12,434

  7. Bus #2

    1. Take the bus from Des Moines to Omahabus bus
    2. Take the bus from Omaha to Saltillobus bus
    3. Take the bus from Saltillo to Terminal Central de Autobuses del Nortebus bus
    4. Take the bus from Terminal Central de Autobuses del Norte to Terminal de Autobuses ADO Cancúnbus bus
    3d 3h

  8. Bus, train

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to San Marcos Amtraktrain train
    3. Take the bus from San Marcos to Terminal Central de Autobuses del Nortebus bus
    4. Take the bus from Terminal Central de Autobuses del Norte to Terminal de Autobuses ADO Cancúnbus bus
    3d 12h
    $10,924–21,718

Des Moines (DSM) to Cancún International Airport (CUN) flights

Calendar38Weekly Planes
Duration7h 2mAverage Duration
Ticket$3,048Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Cancún.ExpandLaunch map view
  • Distance: 2,383.7 km
  • Duration: 6h 50m

What companies run services between Des Moines, IA, USA and Cancún, Mexico?

Delta, United Airlines, and three other airlines fly from Des Moines (DSM) to Cancún International Airport (CUN) 5 times a day. Alternatively, you can take a bus from Des Moines to Cancún via 16th & Jackson NW, Omaha, Monclova, Monterrey, Cárdenas, and Cárdenas in around 2d 18h.

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