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How to get fromDes Moines to Cape Coralby plane, bus (Greyhound, Flixbus), bus, train, car, or taxi

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There are 7 ways to get from Des Moines to Cape Coral by plane, bus (Greyhound, Flixbus), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers

    best
    1. Fly from Des Moines (DSM) to Ft. Myers (RSW)plane plane DSM - RSW
    5h 35m
    $201–876

  2. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    35h 58m
    $247–463

  3. Bus, train, Amtrak Thruway

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Lakeland Amtrak Stationtrain train
    3. Take the bus from Lakeland to Fort Myers, FLbus bus
    2d 7h
    $684–1,413

  4. Drive 1,432 mi

    1. Drive from Des Moines to Cape Coralcar car 1,432 mi
    26h 13m
    $262–378

  5. Fly to Punta Gorda Airport, taxi

    1. Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane plane DSM - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Cape Coraltaxi taxi
    3h 52m
    $268–881

  6. Fly to Sarasota–Bradenton International Airport, bus

    1. Fly from Des Moines (DSM) to Sarasota–Bradenton International Airport (SRQ)plane plane DSM - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    7h 58m
    $252–1,047

  7. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Tampatrain train
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    2d 7h
    $659–1,417

Des Moines to Cape Coral by bus

Calendar7Weekly Buses
Duration35h 58mAverage Duration
Ticket$247Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Cape Coral.ExpandLaunch map view
  • Distance: 1,261.5 mi
  • Duration: 5h 35m

What companies run services between Des Moines, IA, USA and Cape Coral, FL, USA?

Allegiant Air, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Des Moines to Cc Pwky @ Vincennes Blvd via St Louis Bus Station, Atlanta Bus Station, Tampa Bus Station, and Rosa Parks Transportation Ctr in around 35h 58m.

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