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How to get fromDes Moines to Carbondaleby plane, car, bus, train, or bus (Greyhound, Amtrak, Flixbus)

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There are 6 ways to get from Des Moines to Carbondale by plane, car, bus, train, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barkley Regional Airport, drive

    best
    1. Fly from Des Moines (DSM) to Barkley Regional Airport (PAH)plane plane DSM - PAH
    2. Drive from Barkley Regional Airport (PAH) to Carbondalecar car
    6h 40m
    $140–640

  2. Drive 423.1 mi

    cheapest
    1. Drive from Des Moines to Carbondalecar car 423.1 mi
    8h 41m
    $78–112

  3. Bus, train

    1. Take the bus from Des Moines to Champaignbus bus Btw 1402
    2. Take the train from Champaign-Urbana to Carbondaletrain train City of New Orleans / ...
    11h 14m
    $138–234

  4. Fly to Williamson County Regional Airport

    1. Fly from Des Moines (DSM) to Williamson County Regional Airport (MWA)plane plane DSM - MWA
    4h 25m
    $158–661

  5. Fly to Nashville, bus

    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    7h 19m
    $160–678

  6. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    11h 20m
    $83–177

Des Moines to Carbondale by bus and train

Calendar7Weekly Services
Duration11h 14mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Carbondale.ExpandLaunch map view
  • Distance: 479.6 mi
  • Duration: 6h 40m

What companies run services between Des Moines, IA, USA and Carbondale, IL, USA?

United Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Williamson County Regional Airport (MWA) 3 times a day. Alternatively, you can take a bus from Des Moines to Carbondale via St Louis Bus Station and St. Louis in around 11h 20m.

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