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How to get fromDes Moines to Charlotteby plane, bus, train, car, or bus (Greyhound)

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There are 5 ways to get from Des Moines to Charlotte by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    3h 16m
    $161–774
  2. Bus

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Richmond Bsb, INbus bus
    3. Take the bus from Richmond, IN to N Wilson Rd & Ferrell Pl - Columbusbus bus
    4. Take the bus from Columbus to Charlottebus bus
    26h 5m
    $135–327
  3. Bus, train via Ironville

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland to Charlotte Bus Stationbus bus
    25h 25m
    $194–412
  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    36h 38m
    $373–853
  5. Drive  1,029.4 mi

    1. Drive from Des Moines to Charlottecar car 1,029.4 mi
    17h 40m
    $188–272

Des Moines to Charlotte by bus and train

Calendar3Weekly Services
Duration25h 25mAverage Duration
Ticket$194Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT) every 3 hours. Alternatively, you can take a bus from Des Moines to Charlotte via Indianapolis, IN, Richmond, IN, and Columbus in around 26h 5m.

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