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How to get fromDes Moines to Cheyenneby plane, bus (Greyhound), car, taxi, or bus

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There are 7 ways to get from Des Moines to Cheyenne by plane, bus (Greyhound), car, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Cheyenne Airport

    best
    1. Fly from Des Moines (DSM) to Cheyenne Airport (CYS)plane plane DSM - CYS
    3h 51m
    $114–573

  2. Drive to Fort Dodge Municipal Airport, fly to Cheyenne Airport

    cheapest
    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Cheyenne Airport (CYS)plane plane FOD - CYS
    6h 14m
    $87–415

  3. Bus via Omaha

    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Take the bus from Omaha to Denverbus bus
    3. Take the bus from Denver to Cheyennebus bus
    16h 50m
    $206–273

  4. Drive  628.5 mi

    1. Drive from Des Moines to Cheyennecar car 628.5 mi
    9h 39m
    $115–166

  5. Fly Des Moines to Laramie Regional Airport, taxi

    1. Fly from Des Moines (DSM) to Laramie Regional Airport (LAR)plane plane DSM - LAR
    2. Take the taxi from Laramie-Airport-LAR to Cheyennetaxi taxi
    4h 43m
    $214–693

  6. Fly Des Moines to Denver, bus

    1. Fly from Des Moines (DSM) to Denver (DEN)plane plane DSM - DEN
    2. Take the bus from Denver International Airport Pickups to Warren AFBbus bus
    5h 22m
    $159–663

  7. Bus

    1. Take the bus from Des Moines to Denver Union Stationbus bus Greyhound US0123S
    2. Take the bus from Denver Union Station to Cheyennebus bus Greyhound US0560S
    17h 15m
    $153–228

Des Moines to Cheyenne by bus

Calendar4Weekly Buses
Duration16h 50mAverage Duration
Ticket$206Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Cheyenne.ExpandLaunch map view
  • Distance: 586.7 mi
  • Duration: 3h 51m

What companies run services between Des Moines, IA, USA and Cheyenne, WY, USA?

United Airlines and Southwest Airlines fly from Des Moines (DSM) to Cheyenne Airport (CYS) 4 times a day. Alternatively, you can take a bus from Des Moines to Cheyenne via Omaha and Denver in around 16h 50m.

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