There are 5 ways to get from Des Moines to Cincinnati by plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Covington
best- Fly from Des Moines (DSM) to Covington (CVG)plane DSM - CVG
4h 27m$161–875Bus
cheapest- Take the bus from Des Moines to Indianapolis Union Stationbus Greyhound US0157S
- Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus Detroit / ...
14h 35m$87–193Bus via Dayton
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Dayton Trotwood Bus Stationbus
- Take the bus from Dayton Trotwood Bus Station to Cincinnatibus
14h 25m$97–152Drive 572.5 mi
- Drive from Des Moines to Cincinnaticar 572.5 mi
9h 44m$105–151Fly to Blue Grass Airport, drive
- Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane DSM - LEX
- Drive from Lexington-Airport-LEX to Cincinnaticar
6h 6m$124–596
Des Moines to Cincinnati by bus
Comparing Your Travel Options
The cheapest way to get from Des Moines to Cincinnati is to bus via Dayton which costs $95 - $160 and takes 14h 25m.
The fastest way to get from Des Moines to Cincinnati is to fly which takes 4h 27m and costs $160 - $900.
No, there is no direct bus from Des Moines to Cincinnati. However, there are services departing from Des Moines and arriving at Cincinnati via Indianapolis Union Station and Dayton Trotwood Bus Station. The journey, including transfers, takes approximately 14h 25m.
The distance between Des Moines and Cincinnati is 527 miles. The road distance is 575.8 miles.
The best way to get from Des Moines to Cincinnati without a car is to bus via Dayton which takes 14h 25m and costs $95 - $160.
It takes approximately 4h 27m to get from Des Moines to Cincinnati, including transfers.
Des Moines to Cincinnati bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Cincinnati is to fly which takes 4h 27m and costs $160 - $900. Alternatively, you can bus via Dayton, which costs $95 - $160 and takes 14h 25m.
Des Moines to Cincinnati bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Cincinnati is 1h ahead of Des Moines. It is currently 1:35 PM in Des Moines and 2:35 PM in Cincinnati.
What companies run services between Des Moines, IA, USA and Cincinnati, OH, USA?
Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Covington (CVG) hourly. Alternatively, you can take a bus from Des Moines to Cincinnati via Indianapolis Union Station and Dayton Trotwood Bus Station in around 14h 25m.
- Website
- aa.com
Flights from Des Moines to Covington via Chicago O'Hare
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $140–850
Flights from Des Moines to Covington via Charlotte
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Des Moines to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $90–550
Flights from Des Moines to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Blue Grass Airport via Charlotte
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- Greyhound
Bus from Indianapolis Union Station to Dayton Trotwood Bus Station
- Ave. Duration
- 2h 5m
- Frequency
- 3 times a day
- Estimated price
- $16–26
- Website
- Greyhound
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between Des Moines to Cincinnati is 576 miles. It takes approximately 9h 44m to drive from Des Moines to Cincinnati.
Book your Des Moines to Cincinnati bus tickets online with Omio and FlixBus.
There are 667+ hotels available in Cincinnati.


