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How to get fromDes Moines to Clarksvilleby plane, bus, bus (Greyhound, Flixbus), car, or train

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There are 5 ways to get from Des Moines to Clarksville by plane, bus, bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Nashville, bus

    best
    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2. Take the bus from Nashville Bus Station to Clarksville Park & Ridebus bus
    4h 28m
    $166–676

  2. Drive 581.4 mi

    cheapest
    1. Drive from Des Moines to Clarksvillecar car 581.4 mi
    11h 28m
    $107–154

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St Louis Bus Station to Clarksville Park & Ridebus bus Greyhound US0186 / ...
    15h 14m
    $138–252

  4. Fly to Barkley Regional Airport, drive

    1. Fly from Des Moines (DSM) to Barkley Regional Airport (PAH)plane plane DSM - PAH
    2. Drive from Barkley Regional Airport (PAH) to Clarksvillecar car
    7h 9m
    $146–648

  5. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Carbondaletrain train
    3. Take the bus from Carbondale Intermodal Station to Clarksville Park & Ridebus bus
    15h 38m
    $167–309

Des Moines (DSM) to Nashville (BNA) flights

Calendar12Weekly Planes
Duration3h 17mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Clarksville.ExpandLaunch map view
  • Distance: 593.8 mi
  • Duration: 4h 28m

What companies run services between Des Moines, IA, USA and Clarksville, TN, USA?

You can take a bus from Des Moines to Clarksville via St Louis Bus Station and Clarksville Park & Ride in around 15h 14m.

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