Rome2Rio

How to get fromDes Moines to Clarksvilleby plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)

Find Transport to Clarksville

See all options

There are 7 ways to get from Des Moines to Clarksville by plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Nashville, bus

    best
    1. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    2. Take the bus from Nashville Bus Station to Clarksville Park & Ridebus bus
    4h 26m
    $140–576

  2. Drive  581.4 mi

    cheapest
    1. Drive from Des Moines to Clarksvillecar car 581.4 mi
    11h 28m
    $107–154

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Clarksville Park & Ridebus bus
    15h 24m
    $158–277

  4. Bus, train via Chicago

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carbondaletrain train
    4. Take the bus from Carbondale Intermodal Station to Clarksville Park & Ridebus bus
    19h 14m
    $207–434

  5. Fly to Barkley Regional Airport, drive

    1. Fly from Des Moines (DSM) to Barkley Regional Airport (PAH)plane plane DSM - PAH
    2. Drive from Barkley Regional Airport (PAH) to Clarksvillecar car
    7h 9m
    $121–528

  6. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Carbondaletrain train
    3. Take the bus from Carbondale Intermodal Station to Clarksville Park & Ridebus bus
    15h 38m
    $154–296

  7. Bus via Indianapolis (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Clarksville Park & Ridebus bus Greyhound US0112
    16h 59m
    $149–272

Des Moines (DSM) to Nashville (BNA) flights

Calendar9Weekly Planes
Duration3h 25mAverage Duration
Ticket$87Cheapest Price
See schedules

Questions & Answers

Map of how to get from Des Moines to Clarksville.ExpandLaunch map view
  • Distance: 593.8 mi
  • Duration: 4h 26m

What companies run services between Des Moines, IA, USA and Clarksville, TN, USA?

You can take a bus from Des Moines to Clarksville via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Clarksville Park & Ride in around 15h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers