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How to get fromDes Moines to Columbiaby bus (Greyhound), car, or plane

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There are 5 ways to get from Des Moines to Columbia by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus Greyhound US0156
    2. Take the bus from Kansas City Bus Station to Columbiabus bus Greyhound US0175s
    6h 35m
    $48–95
  2. Drive 225.5 mi

    cheapest
    1. Drive from Des Moines to Columbiacar car 225.5 mi
    4h 44m
    $42–60
  3. Fly from Des Moines

    1. Fly from Des Moines (DSM) to Columbia Regional Airport (COU)plane plane DSM - COU
    4h 33m
    $168–686
  4. Bus via Des Moines

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson Lines 803 / ...
    2. Take the bus from Kansas City Bus Station to Columbiabus bus Greyhound US0175s
    6h 50m
    $72–112
  5. Drive to Fort Dodge Municipal Airport, fly

    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Columbia Regional Airport (COU)plane plane FOD - COU
    13h 46m
    $137–459

Des Moines to Columbia by bus (Greyhound)

Calendar12Weekly Buses
Duration6h 35mAverage Duration
Ticket$48Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Columbia, MO, USA?

You can take a bus from Des Moines to Columbia via Kansas City Bus Station in around 6h 35m. Alternatively, American Airlines and United Airlines fly from Des Moines (DSM) to Columbia Regional Airport (COU) every 3 hours.

Airlines
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