There are 6 ways to get from Des Moines to Columbia by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Columbia
best- Fly from Des Moines (DSM) to Columbia (CAE)plane DSM - CAE
6h$360–1,723Drive 1,049.3 mi
cheapest- Drive from Des Moines to Columbiacar 1,049.3 mi
18h 51m$192–277Bus
- Take the bus from Des Moines to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Camdenbus
- Take the bus from Camden to Columbia, SCbus Nyc
29h 26m$214–407Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the train from Chicago Union Station to Columbia Stationtrain Floridian
36h 59m$461–946Fly to Augusta Regional Airport At Bush Field, bus
- Fly from Des Moines (DSM) to Augusta Regional Airport At Bush Field (AGS)plane DSM - AGS
- Take the bus from Augusta to Columbia, SCbus
7h 51m$209–753Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Columbia Stationtrain
38h 10m$492–1,020
Des Moines to Columbia by bus, foot, and train
Questions & Answers
The cheapest way to get from Des Moines to Columbia is to drive which costs $190 - $280 and takes 18h 51m.
The fastest way to get from Des Moines to Columbia is to fly which takes 6h and costs $360 - $1,800.
No, there is no direct bus from Des Moines to Columbia. However, there are services departing from Des Moines and arriving at Sumter Laurel South via St Louis Bus Station, Atlanta Bus Station, Camden and Broad Marley South. The journey, including transfers, takes approximately 29h 26m.
The distance between Des Moines and Columbia is 881 miles. The road distance is 1055.4 miles.
The best way to get from Des Moines to Columbia without a car is to bus which takes 29h 26m and costs $210 - $410.
It takes approximately 6h to get from Des Moines to Columbia, including transfers.
Des Moines to Columbia bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Columbia is to fly which takes 6h and costs $360 - $1,800. Alternatively, you can bus, which costs $210 - $410 and takes 29h 26m.
Des Moines to Columbia bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Columbia is 1h ahead of Des Moines. It is currently 12:52 PM in Des Moines and 1:52 PM in Columbia.
What companies run services between Des Moines, IA, USA and Columbia, SC, USA?
Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Columbia (CAE) every 2 hours. Alternatively, you can take a bus from Des Moines to Sumter Laurel South via St Louis Bus Station, Atlanta Bus Station, Camden, Columbia, SC, and Broad Marley South in around 29h 26m.
- Website
- aa.com
Flights from Des Moines to Columbia via Charlotte
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $340–1,700
Flights from Des Moines to Columbia via Chicago O'Hare
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $360–1,700
Flights from Des Moines to Columbia via Dallas/Ft.Worth
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $500–2,200
Flights from Des Moines to Columbia via New York La Guardia
- Ave. Duration
- 6h 47m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $500–2,300
Flights from Des Moines to Columbia via Reagan Washington
- Ave. Duration
- 8h 5m
- When
- Sunday and Saturday
- Estimated price
- $440–2,000
Flights from Des Moines to Augusta Regional Airport At Bush Field via Charlotte
- Ave. Duration
- 5h 34m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
Flights from Des Moines to Augusta Regional Airport At Bush Field via Reagan Washington
- Ave. Duration
- 6h 19m
- When
- Sunday
- Estimated price
- $180–800
Flights from Des Moines to Augusta Regional Airport At Bush Field via Dallas/Ft.Worth
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $190–850
- Website
- delta.com
Flights from Des Moines to Columbia via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $350–1,700
Flights from Des Moines to Columbia via New York La Guardia
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $500–2,300
Flights from Des Moines to Augusta Regional Airport At Bush Field via Atlanta
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Des Moines to Columbia via Chicago O'Hare
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $360–1,700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Columbia Station
- Ave. Duration
- 28h 45m
- Frequency
- Once daily
- Estimated price
- $410–850
- Website
- https://www.amtrak.com/home.html
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $50–110
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Columbia Station
- Ave. Duration
- 28h 45m
- Frequency
- Once daily
- Estimated price
- $410–850
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Camden
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- 5 times a week
- Estimated price
- $90–160
- Schedules at
- flixbus.com
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from Camden to Columbia, SC
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $28–40
Bus from Augusta to Columbia, SC
- Ave. Duration
- 1h 34m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $30–45
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More Questions & Answers
Yes, the driving distance between Des Moines to Columbia is 1055 miles. It takes approximately 18h 51m to drive from Des Moines to Columbia.
There are 405+ hotels available in Columbia.






