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How to get fromDes Moines to Columbusby plane, bus (Greyhound), car, bus (Greyhound, Flixbus), bus, or train

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There are 5 ways to get from Des Moines to Columbus by plane, bus (Greyhound), car, bus (Greyhound, Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to John Glenn Columbus International Airport (CMH)plane plane DSM - CMH
    4h 47m
    $170–874

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Columbusbus bus Greyhound US0421
    15h 20m
    $97–186

  3. Drive 619.4 mi

    1. Drive from Des Moines to Columbuscar car 619.4 mi
    11h 28m
    $113–164

  4. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus 2511 / ...
    15h 25m
    $105–190

  5. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Toledotrain train
    4. Take the bus from Toledo to Columbus - Mound Stbus bus
    17h 14m
    $171–369

Des Moines to Columbus by bus (Greyhound)

Calendar14Weekly Buses
Duration15h 20mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Columbus.ExpandLaunch map view
  • Distance: 593 mi
  • Duration: 4h 47m

What companies run services between Des Moines, IA, USA and Columbus, OH, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to John Glenn Columbus International Airport (CMH) hourly. Alternatively, you can take a bus from Des Moines to Columbus via Indianapolis Union Station in around 15h 20m.

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