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How to get fromDes Moines to Destinby plane, bus, taxi, train, or car

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There are 8 ways to get from Des Moines to Destin by plane, bus, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport

    best
    1. Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane plane DSM - VPS
    4h 31m
    $168–676

  2. Fly to Dothan Regional Airport, drive

    cheapest
    1. Fly from Des Moines (DSM) to Dothan Regional Airport (DHN)plane plane DSM - DHN
    2. Drive from Dothan Regional Airport (DHN) to Destincar car
    7h 16m
    $148–651

  3. Bus, taxi

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    4. Take the bus from La Grange Bus Station to Mobilebus bus
    5. Take the bus from Loxley to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    30h 48m
    $341–539

  4. Bus, train, taxi via Champaign

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    31h 59m
    $446–866

  5. Drive 1,053.9 mi

    1. Drive from Des Moines to Destincar car 1,053.9 mi
    19h 29m
    $193–278

  6. Fly to Northwest Florida Beaches International Airport, taxi

    1. Fly from Des Moines (DSM) to Northwest Florida Beaches International Airport (ECP)plane plane DSM - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 47m
    $278–801

  7. Fly to Pensacola International Airport, taxi

    1. Fly from Des Moines (DSM) to Pensacola International Airport (PNS)plane plane DSM - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 16m
    $238–731

  8. Bus, train, taxi

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain train
    4. Take the bus from Pascagoula to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    33h 21m
    $321–551

Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar37Weekly Planes
Duration5h 3mAverage Duration
Ticket$119Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Destin.ExpandLaunch map view
  • Distance: 881.9 mi
  • Duration: 4h 31m

What companies run services between Des Moines, IA, USA and Destin, FL, USA?

Delta, American Airlines, and two other airlines fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS) 5 times a day.

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