What is the cheapest way to get from Des Moines to Durham?

The cheapest way to get from Des Moines to Durham is to bus which costs $150 - $320 and takes 28h 55m.

What is the fastest way to get from Des Moines to Durham?

The fastest way to get from Des Moines to Durham is to fly which takes 5h 46m and costs $150 - $700.

Is there a direct bus between Des Moines and Durham?

No, there is no direct bus from Des Moines to Durham. However, there are services departing from Des Moines and arriving at Durham via Indianapolis Union Station, Columbus and Winston Salem(Trans Center). The journey, including transfers, takes approximately 28h 55m.

How far is it from Des Moines to Durham?

The distance between Des Moines and Durham is 919 miles. The road distance is 1059.5 miles.

How do I travel from Des Moines to Durham without a car?

The best way to get from Des Moines to Durham without a car is to bus which takes 28h 55m and costs $150 - $320.

How long does it take to get from Des Moines to Durham?

It takes approximately 5h 46m to get from Des Moines to Durham, including transfers.

Where do I catch the Des Moines to Durham bus from?

Des Moines to Durham bus services, operated by Greyhound USA, depart from Des Moines station.

Bus or fly from Des Moines to Durham?

The best way to get from Des Moines to Durham is to fly which takes 5h 46m and costs $150 - $700. Alternatively, you can bus, which costs $150 - $320 and takes 28h 55m.

Where does the Des Moines to Durham bus arrive?

Des Moines to Durham bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.

What is the time difference between Des Moines and Durham?

Durham is 1h ahead of Des Moines. It is currently 3:32 AM in Des Moines and 4:32 AM in Durham.

Can I drive from Des Moines to Durham?

Yes, the driving distance between Des Moines to Durham is 1060 miles. It takes approximately 18h 17m to drive from Des Moines to Durham.

How do I get a bus ticket from Des Moines to Durham?

Book your Des Moines to Durham bus tickets online with Omio and FlixBus.

Where can I stay near Durham?

There are 403+ hotels available in Durham.

Des Moines to Durham - 7 ways to travel via train, plane, bus, and car

How to get fromDes Moines to Durham

Travel from

See all options

Search accommodation with Expedia

There are 7 ways to get from Des Moines to Durham by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Raleigh-Durham International Airport
best
1. Fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU)plane DSM - RDU
5h 46m
$154–677
Bus (Greyhound)
1. Take the bus from Des Moines to Indianapolis Union Stationbus
2. Take the bus from Indianapolis Union Station to Columbusbus
3. Take the bus from Columbus to Winston Salem(Trans Center)bus
4. Take the bus from Winston Salem(Trans Center) to Durhambus
28h 55m
$156–315
Bus, train
1. Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
2. Take the train from Chicago Union Station to Raleigh Union Stationtrain Floridian
33h 53m
$330–742
Drive 1,053.4 mi
1. Drive from Des Moines to Durhamcar 1,053.4 mi
18h 17m
$193–278
Fly to Piedmont Triad International Airport, train
1. Fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO)plane DSM - GSO
2. Take the train from Greensboro to Durham Amtrak Stationtrain
6h 52m
$241–1,041
Fly to Charlotte Douglas International Airport, train
1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane DSM - CLT
2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
7h 19m
$197–867
Bus, train via Galesburg
1. Take the bus from Des Moines to Galesburgbus
2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
3. Take the train from Chicago Union Station to Raleigh Union Stationtrain
4. Take the train from Raleigh Union Station to Durham Amtrak Stationtrain
34h 56m
$356–821

Des Moines to Durham by bus (Greyhound)

7Weekly Buses

28h 55mAverage Duration

$156Cheapest Price

See schedules

Questions & Answers

Map of how to get from Des Moines to Durham.

Launch map view

Distance: 913.3 mi
Duration: 5h 46m

What companies run services between Des Moines, IA, USA and Durham, NC, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU) hourly. Alternatively, you can take a bus from Des Moines to Durham via Indianapolis Union Station, Columbus, and Winston Salem(Trans Center) in around 28h 55m.

Airlines

Train operators

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.