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How to get fromDes Moines to Edwardsvilleby plane, taxi, bus (Greyhound), car, bus, or train

Find Transport to Edwardsville

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There are 5 ways to get from Des Moines to Edwardsville by plane, taxi, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport, taxi

    best
    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    2. Take the taxi from St-Louis-Airport-STL to Edwardsvilletaxi taxi
    4h 37m
    $228–906

  2. Drive 325.3 mi

    cheapest
    1. Drive from Des Moines to Edwardsvillecar car 325.3 mi
    7h 24m
    $60–86

  3. Bus (Greyhound)

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    8h 46m
    $117–189

  4. Fly to Decatur Airport, drive

    1. Fly from Des Moines (DSM) to Decatur Airport (DEC)plane plane DSM - DEC
    2. Drive from Decatur Airport (DEC) to Edwardsvillecar car
    6h 25m
    $126–598

  5. Bus, train

    1. Take the bus from Des Moines to Bloomington-Normalbus bus Greyhound US0157S
    2. Take the train from Bloomington-Normal to Alton Stationtrain train Texas Eagle / ...
    9h 52m
    $122–222

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar134Weekly Planes
Duration5h 27mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Edwardsville.ExpandLaunch map view
  • Distance: 295.5 mi
  • Duration: 4h 37m

What companies run services between Des Moines, IA, USA and Edwardsville, IL, USA?

Greyhound USA operates a bus from Des Moines to St Louis Bus Station once daily. Tickets cost $65–130 and the journey takes 8h 15m.

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