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How to get fromDes Moines to Effinghamby bus, train, car, plane, or bus (Greyhound)

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There are 8 ways to get from Des Moines to Effingham by bus, train, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus Greyhound US0157S
    2. Take the train from Champaign-Urbana to Effingham Stationtrain train Saluki / ...
    9h 32m
    $71–139

  2. Drive 376.2 mi

    cheapest
    1. Drive from Des Moines to Effinghamcar car 376.2 mi
    8h 15m
    $69–100

  3. Fly to University Of Illinois Willard Airport, train

    1. Fly from Des Moines (DSM) to University Of Illinois Willard Airport (CMI)plane plane DSM - CMI
    2. Take the train from Champaign-Urbana to Effingham Stationtrain train
    7h 20m
    $127–529

  4. Bus (Greyhound)

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St Louis Bus Station to Effinghambus bus Greyhound US0421
    11h 5m
    $75–143

  5. Fly to Chicago Midway International Airport, train

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the train from Chicago Union Station to Effingham Stationtrain train
    7h 5m
    $138–549

  6. Fly to Chicago O'Hare International Airport, train

    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the train from Chicago Union Station to Effingham Stationtrain train
    7h 27m
    $125–496

  7. Fly to Decatur Airport, bus, train

    1. Fly from Des Moines (DSM) to Decatur Airport (DEC)plane plane DSM - DEC
    2. Take the bus from Decatur Downtown Transportation Center to Champaign Intermodal Trans Ctrbus bus
    3. Take the train from Champaign-Urbana to Effingham Stationtrain train
    8h 28m
    $134–535

  8. Fly to Abraham Lincoln Capital Airport, bus, train

    1. Fly from Des Moines (DSM) to Abraham Lincoln Capital Airport (SPI)plane plane DSM - SPI
    2. Take the bus from Springfield SMTD Transfer Center to Champaign Intermodal Trans Ctrbus bus
    3. Take the train from Champaign-Urbana to Effingham Stationtrain train
    8h 33m
    $140–554

Des Moines to Effingham by bus and train

Calendar7Weekly Services
Duration9h 32mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Effingham.ExpandLaunch map view
  • Distance: 413.4 mi
  • Duration: 9h 32m

What companies run services between Des Moines, IA, USA and Effingham, IL, USA?

You can take a bus from Des Moines to Effingham via St Louis Bus Station in around 11h 5m.

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