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How to get fromDes Moines to Farmingtonby bus, taxi, car, plane, or train

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There are 6 ways to get from Des Moines to Farmington by bus, taxi, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the taxi from 4103 Lemay Ferry Wb to Farmingtontaxi taxi
    10h 30m
    $194–279

  2. Drive 383.7 mi

    cheapest
    1. Drive from Des Moines to Farmingtoncar car 383.7 mi
    7h 42m
    $70–102

  3. Fly to Lambert–St. Louis International Airport, train

    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    2. Take the train from St. Louis to Arcadia Valley Stationtrain train
    8h 22m
    $234–939

  4. Bus, train

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the train from St. Louis to Arcadia Valley Stationtrain train Texas Eagle
    11h 59m
    $136–233

  5. Fly to Cape Girardeau Municipal Airport, drive

    1. Fly from Des Moines (DSM) to Cape Girardeau Municipal Airport (CGI)plane plane DSM - CGI
    2. Drive from Cape Girardeau Municipal Airport (CGI) to Farmingtoncar car
    6h 44m
    $301–1,041

  6. Fly to Williamson County Regional Airport, drive

    1. Fly from Des Moines (DSM) to Williamson County Regional Airport (MWA)plane plane DSM - MWA
    2. Drive from Williamson County Regional Airport (MWA) to Farmingtoncar car
    6h 24m
    $135–597

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar134Weekly Planes
Duration5h 27mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Farmington.ExpandLaunch map view
  • Distance: 485.9 mi
  • Duration: 10h 30m

What companies run services between Des Moines, IA, USA and Farmington, MO, USA?

There is no direct connection from Des Moines to Farmington. However, you can take the bus to St Louis Bus Station, walk to Civic Center Transit Center, take the line 73 bus to 4103 Lemay Ferry Wb, then take the taxi to Farmington. Alternatively, you can drive from Des Moines to Farmington in around 7h 42m.

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