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How to get fromDes Moines to Frankfortby plane, car, bus, taxi, or train

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There are 8 ways to get from Des Moines to Frankfort by plane, car, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Louisville International Airport, drive

    best
    1. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    2. Drive from Louisville-Airport-SDF to Frankfortcar car
    4h 45m
    $157–786

  2. Bus, drive

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Louisville, KY to Frankfortcar car
    14h 5m
    $100–191

  3. Drive 612.8 mi

    1. Drive from Des Moines to Frankfortcar car 612.8 mi
    11h 18m
    $112–162

  4. Fly Des Moines to Blue Grass Airport

    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    4h 59m
    $273–1,206

  5. Fly Des Moines to Covington, drive

    1. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    2. Drive from Covington (CVG) to Frankfortcar car
    5h 12m
    $161–791

  6. Drive to Fort Dodge Municipal Airport, fly to Blue Grass Airport

    1. Drive from Des Moines to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Blue Grass Airport (LEX)plane plane FOD - LEX
    8h 9m
    $232–959

  7. Bus, taxi

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to El Mercadito Grocery - Clarksville, INbus bus
    3. Take the taxi from Middletown Station @ Target to Frankforttaxi taxi
    17h 47m
    $227–416

  8. Bus, train, drive

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    5. Drive from Louisville, KY to Frankfortcar car
    18h 44m
    $172–358

Des Moines (DSM) to Louisville International Airport (SDF) flights

Calendar110Weekly Planes
Duration5h 27mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Frankfort.ExpandLaunch map view
  • Distance: 538.9 mi
  • Duration: 4h 45m

What companies run services between Des Moines, IA, USA and Frankfort, KY, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Blue Grass Airport (LEX) hourly.

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