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How to get fromDes Moines to Granite Cityby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

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There are 6 ways to get from Des Moines to Granite City by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    4h 48m
    $121–530

  2. Drive  332.5 mi

    cheapest
    1. Drive from Des Moines to Granite Citycar car 332.5 mi
    6h 44m
    $61–88

  3. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson Lines 803 / ...
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus Greyhound US0180s / ...
    8h 43m
    $112–161

  4. Bus, train via Kansas City

    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus Greyhound US0156
    2. Take the train from Kansas City to St. Louistrain train Missouri River Runner / ...
    10h 49m
    $204–314

  5. Bus, train

    1. Take the bus from Des Moines to Bloomington-Normalbus bus Greyhound US0157S
    2. Take the train from Bloomington-Normal to St. Louistrain train Lincoln Service / ...
    10h 8m
    $156–239

  6. Bus

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus bus
    10h 59m

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar125Weekly Planes
Duration5hAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Granite City.ExpandLaunch map view
  • Distance: 288 mi
  • Duration: 4h 48m

What companies run services between Des Moines, IA, USA and Granite City, IL, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Des Moines to Granite City via Kansas City, Kansas City Bus Station, and St Louis Bus Station in around 8h 43m.

Airlines
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