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How to get fromDes Moines to Greensboroby plane, bus (Greyhound), bus, train, or car

Find Transport to Greensboro

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There are 7 ways to get from Des Moines to Greensboro by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO)plane plane DSM - GSO
    4h 41m
    $132–488

  2. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbusbus bus
    3. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    27h 54m
    $194–288

  3. Bus, train

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Charlottesvilletrain train
    3. Take the train from Charlottesville to Greensborotrain train
    30h 18m
    $503–822

  4. Drive  1,000.9 mi

    1. Drive from Des Moines to Greensborocar car 1,000.9 mi
    17h 23m
    $183–264

  5. Fly to Charlotte Douglas International Airport, train

    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    2. Take the train from Charlotte Amtrak Station to Greensborotrain train
    6h 7m
    $193–809

  6. Bus, train via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    35h 1m
    $650–1,103

  7. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Greensborotrain train
    35h 59m
    $712–1,214

Des Moines to Greensboro by bus and train

Calendar3Weekly Services
Duration30h 18mAverage Duration
Ticket$503Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Greensboro.ExpandLaunch map view
  • Distance: 844.4 mi
  • Duration: 4h 41m

What companies run services between Des Moines, IA, USA and Greensboro, NC, USA?

American Airlines, United Airlines, and Delta fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO) every 3 hours. Alternatively, you can take a bus from Des Moines to W Washington & Greene via Indianapolis Union Station, Columbus, Winston Salem(Trans Center), Winston-Salem Transportation Center, and Coble Transportation Center in around 27h 54m.

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