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How to get fromDes Moines to Greensboroby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 7 ways to get from Des Moines to Greensboro by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO)plane plane DSM - GSO
    4h 45m
    $276–1,156

  2. Drive 1,000.9 mi

    cheapest
    1. Drive from Des Moines to Greensborocar car 1,000.9 mi
    17h 23m
    $183–264

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Greensboro Bus Stopbus bus
    27h
    $201–394

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    34h 6m

  5. Fly to Charlotte Douglas International Airport, train

    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    2. Take the train from Charlotte Amtrak Station to Greensborotrain train
    6h 16m
    $242–1,037

  6. Bus, train via Ironville

    1. Take the bus from Des Moines to Indianapolisbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    27h 9m

  7. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Greensborotrain train
    35h 59m

Des Moines to Greensboro by bus

Calendar7Weekly Buses
Duration27hAverage Duration
Ticket$201Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Greensboro.ExpandLaunch map view
  • Distance: 844.4 mi
  • Duration: 4h 45m

What companies run services between Des Moines, IA, USA and Greensboro, NC, USA?

American Airlines, Delta, and United Airlines fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO) every 2 hours. Alternatively, you can take a bus from Des Moines to Greensboro Bus Stop via St Louis Bus Station and Atlanta Bus Station in around 27h.

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