There are 8 ways to get from Des Moines to Greensboro by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Piedmont Triad International Airport
best- Fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO)plane DSM - GSO
4h 51m$127–488Bus
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Greensboro Bus Stopbus
29h$236–371Bus, train
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the train from Indianapolis to Charlottesvilletrain
- Take the train from Charlottesville to Greensborotrain
30h 18m$511–826Drive 1,000.9 mi
- Drive from Des Moines to Greensborocar 1,000.9 mi
17h 23m$177–256Fly to Charlotte Douglas International Airport, train
- Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane DSM - CLT
- Take the train from Charlotte Amtrak Station to Greensborotrain
6h 9m$193–809Fly to Raleigh-Durham International Airport, bus
- Fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU)plane DSM - RDU
- Take the bus from Durham to Greensboro Bus Stopbus
7h 15m$153–644Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Greensborotrain
35h 59m$713–1,216Bus, train via Chicago
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Carytrain
- Take the train from Cary to Greensborotrain
36h 1m$655–1,111
Des Moines to Greensboro by bus
Comparing Your Travel Options
The cheapest way to get from Des Moines to Greensboro is to drive which costs $170 - $260 and takes 17h 23m.
The fastest way to get from Des Moines to Greensboro is to fly which takes 4h 51m and costs $120 - $490.
No, there is no direct bus from Des Moines to Greensboro. However, there are services departing from Des Moines and arriving at Greensboro Bus Stop via Indianapolis Union Station and Atlanta Bus Station. The journey, including transfers, takes approximately 29h.
The distance between Des Moines and Greensboro is 849 miles. The road distance is 1006.7 miles.
The best way to get from Des Moines to Greensboro without a car is to bus which takes 29h and costs $230 - $380.
It takes approximately 4h 51m to get from Des Moines to Greensboro, including transfers.
Des Moines to Greensboro bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Greensboro is to fly which takes 4h 51m and costs $120 - $490. Alternatively, you can bus, which costs $230 - $380 and takes 29h.
Des Moines to Greensboro bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Greensboro is 1h ahead of Des Moines. It is currently 4:40 PM in Des Moines and 5:40 PM in Greensboro.
What companies run services between Des Moines, IA, USA and Greensboro, NC, USA?
Delta, United Airlines, and American Airlines fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO) every 3 hours. Alternatively, you can take a bus from Des Moines to Greensboro Bus Stop via Indianapolis Union Station and Atlanta Bus Station in around 29h.
- Website
- delta.com
Flights from Des Moines to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $90–460
Flights from Des Moines to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 7h 20m
- When
- Every day
- Estimated price
- $90–450
Flights from Des Moines to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $140–750
Flights from Des Moines to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Raleigh-Durham International Airport via Minneapolis
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $140–700
- Website
- aa.com
Flights from Des Moines to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $85–430
Flights from Des Moines to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 16m
- When
- Saturday
- Estimated price
- $95–470
Flights from Des Moines to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $80–430
Flights from Des Moines to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 8h 15m
- When
- Every day
- Estimated price
- $110–550
Flights from Des Moines to Charlotte Douglas International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $120–700
Flights from Des Moines to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $130–700
Flights from Des Moines to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $120–600
Flights from Des Moines to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 5h 17m
- When
- Sunday
- Estimated price
- $130–650
Flights from Des Moines to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $120–600
- Website
- united.com
Flights from Des Moines to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $80–430
Flights from Des Moines to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $130–700
Flights from Des Moines to Raleigh-Durham International Airport via Chicago O'Hare
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $120–600
- Website
- southwest.com
Flights from Des Moines to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Tuesday and Wednesday
- Estimated price
- $130–700
Flights from Des Moines to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Saturday
- Estimated price
- $130–700
Flights from Des Moines to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $120–600
Flights from Des Moines to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
Train from Charlottesville to Greensboro
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Amtrak
Train from Charlotte Amtrak Station to Greensboro
- Ave. Duration
- 1h 32m
- Frequency
- Every 4 hours
- Estimated price
- $50–80
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Raleigh Union Station to Greensboro
- Ave. Duration
- 1h 33m
- Frequency
- 5 times a day
- Estimated price
- $40–70
- Website
- Amtrak
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 26m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Cary to Greensboro
- Ave. Duration
- 1h 21m
- Frequency
- 5 times a day
- Estimated price
- $40–65
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 25m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Indianapolis Union Station to Atlanta Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- Every 4 hours
- Estimated price
- $100–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Greensboro Bus Stop
- Ave. Duration
- 6h 40m
- Frequency
- 4 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 25m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $65–100
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to Greensboro Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Every 4 hours
- Estimated price
- $50–80
- Schedules at
- Flixbus USA
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Des Moines to Greensboro is 1007 miles. It takes approximately 17h 23m to drive from Des Moines to Greensboro.
Book your Des Moines to Greensboro bus tickets online with Omio and FlixBus.
There are 263+ hotels available in Greensboro.






