There are 3 ways to get from Des Moines to Hannibal by bus (Greyhound), car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Des Moines to Quincy Public Transit Hubbus Greyhound US0153S
6h 10m$99–152Drive 216.6 mi
cheapest- Drive from Des Moines to Hannibalcar 216.6 mi
4h 37m$40–58Fly, shuttle
- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
- Take a shuttle bus from St. Louis to Hannibal
7h 14m$192–913
Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Des Moines to Hannibal is to drive which costs $35 - $60 and takes 4h 37m.
The fastest way to get from Des Moines to Hannibal is to drive which takes 4h 37m and costs $35 - $60.
No, there is no direct bus from Des Moines to Hannibal. However, there are services departing from Des Moines and arriving at Quincy Public Transit Hub via . The journey, including transfers, takes approximately 6h 10m.
The distance between Des Moines and Hannibal is 301 miles. The road distance is 217.9 miles.
The best way to get from Des Moines to Hannibal without a car is to bus which takes 6h 10m and costs $95 - $160.
It takes approximately 6h 10m to get from Des Moines to Hannibal, including transfers.
Des Moines to Hannibal bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Hannibal bus services, operated by Greyhound USA, arrive at Quincy Public Transit Hub station.
Yes, the driving distance between Des Moines to Hannibal is 218 miles. It takes approximately 4h 37m to drive from Des Moines to Hannibal.
There are 22+ hotels available in Hannibal.
What companies run services between Des Moines, IA, USA and Hannibal, MO, USA?
Greyhound USA operates a bus from Des Moines to Quincy Public Transit Hub once daily. Tickets cost $40–85 and the journey takes 5h 40m.
- Website
- united.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $140–850
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $270–1,200
- Website
- aa.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $140–850
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $240–1,200
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $140–850
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 30m
- When
- Sunday
- Estimated price
- $270–1,200
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $160–900
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $250–1,200
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Des Moines to Quincy Public Transit Hub
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
- Phone
- +1-888-875-6287
- Website
- oatstransit.org
Shuttle from St. Louis to Hannibal
- Ave. Duration
- 1h 50m
- Frequency
- Twice a week
- Estimated price
- $4–7
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
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