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How to get fromDes Moines to Harlingenby plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

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There are 9 ways to get from Des Moines to Harlingen by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rio Grande Valley International Airport

    best
    1. Fly from Des Moines (DSM) to Rio Grande Valley International Airport (HRL)plane plane DSM - HRL
    5h 59m
    $180–773

  2. Bus via Denton

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to Dentonbus bus
    3. Take the bus from Denton to Dallas Bus Stationbus bus
    4. Take the bus from Dallas Bus Station to Harlingen Bus Stationbus bus
    30h 45m
    $238–392

  3. Bus, train

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to San Marcos Amtraktrain train
    3. Take the bus from San Marcos to Harlingen Bus Stationbus bus
    43h 14m
    $437–874

  4. Drive 1,182.6 mi

    1. Drive from Des Moines to Harlingencar car 1,182.6 mi
    20h 7m
    $216–312

  5. Fly to Mcallen Miller International Airport, bus

    1. Fly from Des Moines (DSM) to Mcallen Miller International Airport (MFE)plane plane DSM - MFE
    2. Take the bus from McAllen Central Station to Harlingenbus bus
    6h 55m
    $245–1,030

  6. Fly to Brownsville-South Padre Island International Airport, bus

    1. Fly from Des Moines (DSM) to Brownsville-South Padre Island International Airport (BRO)plane plane DSM - BRO
    2. Take the bus from Brownsville to Harlingen Bus Stationbus bus
    7h 29m
    $265–1,073

  7. Fly to Corpus Christi International Airport, bus

    1. Fly from Des Moines (DSM) to Corpus Christi International Airport (CRP)plane plane DSM - CRP
    2. Take the bus from Robstown Station to Harlingen Bus Stationbus bus
    7h 34m
    $233–826

  8. Bus

    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Take the bus from Omaha to San Antoniobus bus
    3. Take the bus from San Antonio to Harlingen Bus Stationbus bus
    32h 13m
    $330–369

  9. Bus, train via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the train from St. Louis to San Antonio Stationtrain train
    4. Take the bus from San Antonio to Harlingen Bus Stationbus bus
    44h 17m
    $549–1,062

Des Moines to Harlingen by bus and train

Calendar7Weekly Services
Duration43h 14mAverage Duration
Ticket$437Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Harlingen.ExpandLaunch map view
  • Distance: 1,094.3 mi
  • Duration: 5h 59m

What companies run services between Des Moines, IA, USA and Harlingen, TX, USA?

American Airlines, Delta, and three other airlines fly from Des Moines (DSM) to Rio Grande Valley International Airport (HRL) 4 times a day. Alternatively, you can take a bus from Des Moines to Harlingen Bus Station via Kansas City Bus Station, Denton, and Dallas Bus Station in around 30h 45m.

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