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How to get fromDes Moines to Harpers Ferryby plane, car, bus, or train

Find Transport to Harpers Ferry

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There are 5 ways to get from Des Moines to Harpers Ferry by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, drive

    best
    1. Fly from Des Moines (DSM) to La Crosse (LSE)plane plane DSM - LSE
    2. Drive from La-Crosse-Airport-LSE to Harpers Ferrycar car
    5h 52m
    $123–586

  2. Drive 209.6 mi

    cheapest
    1. Drive from Des Moines to Harpers Ferrycar car 209.6 mi
    4h 23m
    $39–56

  3. Bus, train, drive

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    3. Drive from La Crosse Amtrak Station to Harpers Ferrycar car
    9h 51m
    $114–189

  4. Bus, drive

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the bus from St. Paul to La Crossebus bus
    3. Drive from La Crosse to Harpers Ferrycar car
    10h 20m
    $114–168

  5. Bus, drive via Des Moines

    1. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    2. Take the bus from St. Paul to La Crossebus bus
    3. Drive from La Crosse to Harpers Ferrycar car
    11h 16m
    $86–148

Des Moines (DSM) to La Crosse (LSE) flights

Calendar43Weekly Planes
Duration6h 16mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Harpers Ferry.ExpandLaunch map view
  • Distance: 265.1 mi
  • Duration: 5h 52m

What companies run services between Des Moines, IA, USA and Harpers Ferry, IA, USA?

There is no direct connection from Des Moines to Harpers Ferry. However, you can take the taxi to Des-Moines-Airport-DSM airport, fly to La Crosse (LSE), then drive to Harpers Ferry. Alternatively, you can take a bus from Des Moines to Harpers Ferry via St. Paul, St. Paul-Minneapolis, and La Crosse Amtrak Station in around 9h 51m.

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