Rome2Rio

How to get fromDes Moines to Indianaby plane, train, bus (Greyhound), or car

Find Transport to Indiana

See all options

There are 4 ways to get from Des Moines to Indiana by plane, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport, train

    best
    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    3h 20m
    $74–368
  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    9h 25m
    $70–120
  3. Drive  465.7 mi

    1. Drive from Des Moines to Indianapoliscar car 465.7 mi
    7h 54m
    $85–123
  4. Fly to Chicago Midway International Airport, train

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the train from Museum Campus/11th St. to Gary Metro Centertrain train
    3h 20m
    $89–458

Des Moines to Indiana by bus (Greyhound)

Calendar7Weekly Buses
Duration9h 25mAverage Duration
Ticket$70Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Des Moines, IA, USA and Indiana, USA?

Greyhound USA operates a bus from Des Moines to Indianapolis Union Station once daily. Tickets cost $70–120 and the journey takes 9h 25m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There