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How to get fromDes Moines to Ithacaby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 9 ways to get from Des Moines to Ithaca by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester, bus

    best
    1. Fly from Des Moines (DSM) to Rochester (ROC)plane plane DSM - ROC
    2. Take the bus from Rochester to Ithacabus bus
    7h 17m
    $257–1,200

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    4. Take the bus from Buffalo to Ithacabus bus
    23h 55m
    $125–281

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Rochestertrain train
    3. Take the bus from Rochester to Ithacabus bus 231
    22h 34m
    $262–541

  4. Drive 973.4 mi

    1. Drive from Des Moines to Ithacacar car 973.4 mi
    16h 56m
    $178–257

  5. Fly to Greater Binghamton Airport, bus

    1. Fly from Des Moines (DSM) to Greater Binghamton Airport (BGM)plane plane DSM - BGM
    2. Take the bus from Binghamton to Ithacabus bus
    9h 7m
    $199–751

  6. Fly to Elmira/Corning Regional Airport, bus

    1. Fly from Des Moines (DSM) to Elmira/Corning Regional Airport (ELM)plane plane DSM - ELM
    2. Take the bus from Transit Center - PO Side to Tompkins County Librarybus bus
    8h 32m
    $153–680

  7. Fly to Syracuse Hancock International Airport, bus

    1. Fly from Des Moines (DSM) to Syracuse Hancock International Airport (SYR)plane plane DSM - SYR
    2. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 56m
    $270–1,264

  8. Fly to Laguardia Airport, bus

    1. Fly from Des Moines (DSM) to Laguardia Airport (LGA)plane plane DSM - LGA
    2. Take the bus from New York to Ithacabus bus
    9h 15m
    $256–1,114

  9. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train
    4. Take the bus from Syracuse Bus Station to Ithacabus bus
    24h 32m
    $311–625

Des Moines to Ithaca by bus, foot, and train

Calendar14Weekly Services
Duration22h 34mAverage Duration
Ticket$262Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Ithaca.ExpandLaunch map view
  • Distance: 925.4 mi
  • Duration: 7h 17m

What companies run services between Des Moines, IA, USA and Ithaca, NY, USA?

You can take a bus from Des Moines to Ithaca via Chicago, Cleveland, OH, Buffalo, NY, and Buffalo in around 23h 55m.

Airlines
Train operators
Bus operators

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