There are 10 ways to get from Des Moines to Kalamazoo by plane, bus (Greyhound, Amtrak), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Kalamazoo-Battle Creek International Airport
best- Fly from Des Moines (DSM) to Kalamazoo-Battle Creek International Airport (AZO)plane DSM - AZO
5h 39m$76–375Bus via Chicago
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S / ...
- Take the bus from Chicago Union Station to Kalamazoobus Amtrak Thruway Connecting Service
11h 20mBus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Kalamazootrain
11h 31m$198–316Drive 459.3 mi
- Drive from Des Moines to Kalamazoocar 459.3 mi
7h 43m$79–114Fly to Chicago O'Hare International Airport, train
- Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane DSM - ORD
- Take the train from Chicago Union Station to Kalamazootrain
5h 55m$134–401Fly to Chicago Midway International Airport, train
- Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane DSM - MDW
- Take the train from Chicago Union Station to Kalamazootrain
5h 30m$146–498Fly to Gerald R. Ford International Airport, bus
- Fly from Des Moines (DSM) to Gerald R. Ford International Airport (GRR)plane DSM - GRR
- Take the bus from Grand Rapids to Kalamazoobus
7h 47m$88–401Fly to Detroit, train
- Fly from Des Moines (DSM) to Detroit (DTW)plane DSM - DTW
- Take the train from Dearborn to Kalamazootrain
6h 20m$181–695Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S / ...
- Take the train from Chicago Union Station to Kalamazootrain Wolverine / ...
11h 20m$140–215Bus (Greyhound)
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S / ...
- Take the bus from Chicago Bus Station to Kalamazoo Bus Stopbus Greyhound US0160
12h$92–135
Des Moines (DSM) to Kalamazoo-Battle Creek International Airport (AZO) flights
Comparing Your Travel Options
The cheapest way to get from Des Moines to Kalamazoo is to drive which costs $75 - $120 and takes 7h 43m.
The fastest way to get from Des Moines to Kalamazoo is to fly and train which takes 5h 30m and costs $140 - $500.
No, there is no direct bus from Des Moines to Kalamazoo. However, there are services departing from Des Moines and arriving at Kalamazoo via Chicago Union Station. The journey, including transfers, takes approximately 11h 20m.
The distance between Des Moines and Kalamazoo is 438 miles. The road distance is 462 miles.
The best way to get from Des Moines to Kalamazoo without a car is to bus via Chicago which takes 11h 20m and costs .
It takes approximately 5h 39m to get from Des Moines to Kalamazoo, including transfers.
Des Moines to Kalamazoo bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Kalamazoo is to fly which takes 5h 39m and costs $75 - $380. Alternatively, you can bus via Chicago, which costs and takes 11h 20m.
Des Moines to Kalamazoo bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Kalamazoo is 1h ahead of Des Moines. It is currently 11:39 AM in Des Moines and 12:39 PM in Kalamazoo.
What companies run services between Des Moines, IA, USA and Kalamazoo, MI, USA?
Delta and American Airlines fly from Des Moines (DSM) to Kalamazoo-Battle Creek International Airport (AZO) every 4 hours. Alternatively, you can take a bus from Des Moines to Kalamazoo via Chicago Bus Station and Chicago Union Station in around 11h 20m.
- Website
- delta.com
Flights from Des Moines to Kalamazoo-Battle Creek International Airport via Detroit
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $70–390
Flights from Des Moines to Kalamazoo-Battle Creek International Airport via Minneapolis, Detroit
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $80–430
Flights from Des Moines to Gerald R. Ford International Airport via Detroit
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $70–390
Flights from Des Moines to Gerald R. Ford International Airport via Atlanta
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $110–550
Flights from Des Moines to Gerald R. Ford International Airport via Minneapolis
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $65–380
Flights from Des Moines to Detroit
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $90–550
Flights from Des Moines to Detroit via Minneapolis
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $35–250
Flights from Des Moines to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $55–350
Flights from Des Moines to Detroit via Chicago O'Hare International Airport
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $90–550
- Website
- aa.com
Flights from Des Moines to Kalamazoo-Battle Creek International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $55–350
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $35–250
Flights from Des Moines to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $55–350
- Website
- southwest.com
Flights from Des Moines to Chicago Midway International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $50–350
Flights from Des Moines to Gerald R. Ford International Airport via Chicago Midway International Airport
- Ave. Duration
- 5h 17m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $55–350
Flights from Des Moines to Detroit via Chicago Midway International Airport
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $90–550
- Website
- allegiantair.com
Flights from Des Moines to Gerald R. Ford International Airport via Nashville
- Ave. Duration
- 5h 11m
- When
- Monday
- Estimated price
- $90–450
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Dearborn to Kalamazoo
- Ave. Duration
- 2h 29m
- Frequency
- 3 times a day
- Estimated price
- $70–120
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Chicago Bus Station to Kalamazoo Bus Stop
- Ave. Duration
- 2h 55m
- Frequency
- 5 times a day
- Estimated price
- $27–40
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 3 times a week
- Website
- Amtrak
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Grand Rapids to Kalamazoo
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–24
- Website
- Indian Trails
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Booking & Getting There
Yes, the driving distance between Des Moines to Kalamazoo is 462 miles. It takes approximately 7h 43m to drive from Des Moines to Kalamazoo.
Book your Des Moines to Kalamazoo bus tickets online with Omio.
There are 53+ hotels available in Kalamazoo.








