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How to get fromDes Moines to LaSalleby bus, train, taxi, car, or plane

Find Transport to LaSalle

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There are 4 ways to get from Des Moines to LaSalle by bus, train, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train, taxi

    best
    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Mendota Stationtrain train
    3. Take the taxi from Mendota Station to LaSalletaxi taxi
    7h 14m
    $125–198

  2. Drive 259.9 mi

    cheapest
    1. Drive from Des Moines to LaSallecar car 259.9 mi
    4h 21m
    $48–69

  3. Fly to Chicago Midway International Airport, train, taxi

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the train from Chicago Union Station to Mendota Stationtrain train
    3. Take the taxi from Mendota Station to LaSalletaxi taxi
    5h 18m
    $178–569

  4. Fly to Chicago O'Hare International Airport, train, taxi

    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the train from Chicago Union Station to Mendota Stationtrain train
    3. Take the taxi from Mendota Station to LaSalletaxi taxi
    5h 41m
    $165–506

Des Moines (DSM) to Chicago Midway International Airport (MDW) flights

Calendar14Weekly Planes
Duration1h 19mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to LaSalle.ExpandLaunch map view
  • Distance: 311.8 mi
  • Duration: 7h 14m

What companies run services between Des Moines, IA, USA and LaSalle, IL, USA?

There is no direct connection from Des Moines to LaSalle. However, you can take the bus to Galesburg, walk to Galesburg Amtrak Station, take the train to Mendota Station, then take the taxi to LaSalle. Alternatively, you can drive from Des Moines to LaSalle in around 4h 21m.

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