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How to get fromDes Moines to Lafayetteby plane, bus (Greyhound), bus, train, or car

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There are 5 ways to get from Des Moines to Lafayette by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Lafayette Regional Airport (LFT)plane plane DSM - LFT
    4h 48m
    $169–734

  2. Drive 896.5 mi

    cheapest
    1. Drive from Des Moines to Lafayettecar car 896.5 mi
    16h 52m
    $164–237

  3. Bus via Wake Village

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Texarkanabus bus
    3. Take the bus from Texarkana to Shreveport Bus Stationbus bus
    4. Take the bus from Shreveport Bus Station to Lafayette Transit Systembus bus
    22h 25m
    $214–333

  4. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Lafayette Amtrak Stationtrain train
    29h 41m
    $346–747

  5. Bus (Greyhound)

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Baton Rouge Bus Stationbus bus
    3. Take the bus from Baton Rouge Bus Station to Lafayette Transit Systembus bus
    29h 55m
    $180–364

Des Moines to Lafayette by bus

Calendar11Weekly Buses
Duration22h 25mAverage Duration
Ticket$214Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Lafayette.ExpandLaunch map view
  • Distance: 797.4 mi
  • Duration: 4h 48m

What companies run services between Des Moines, IA, USA and Lafayette, LA, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Lafayette Regional Airport (LFT) every 4 hours. Alternatively, you can take a bus from Des Moines to Lafayette Transit System via Kansas City, Texarkana, and Shreveport Bus Station in around 22h 25m.

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