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How to get fromDes Moines to Lexingtonby plane, car, bus, or taxi

Find Transport to Lexington

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There are 7 ways to get from Des Moines to Lexington by plane, car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Covington, drive

    best
    1. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    5h 8m
    $173–843

  2. Bus, drive

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    17h 34m
    $108–202

  3. Drive 648.5 mi

    1. Drive from Des Moines to Lexingtoncar car 648.5 mi
    11h 15m
    $119–171

  4. Fly to Louisville International Airport, drive

    1. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 17m
    $162–792

  5. Fly to Blue Grass Airport

    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    6h 42m
    $230–1,223

  6. Bus, taxi, drive

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Paoli Walmartbus bus
    3. Take the taxi from Paoli Walmart to Indiana University Southeasttaxi taxi
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    18h 45m
    $226–342

  7. Bus, drive via St. Louis

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Corydon, INbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    18h 59m
    $193–316

Des Moines (DSM) to Covington (CVG) flights

Calendar116Weekly Planes
Duration4h 56mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Lexington.ExpandLaunch map view
  • Distance: 592.1 mi
  • Duration: 5h 8m

What companies run services between Des Moines, IA, USA and Lexington, KY, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Blue Grass Airport (LEX) hourly.

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