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How to get fromDes Moines to Lexingtonby plane, car, bus, or taxi

Find Transport to Lexington

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There are 6 ways to get from Des Moines to Lexington by plane, car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Covington, drive

    best
    1. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    5h 8m
    $134–645

  2. Fly to Blue Grass Airport

    cheapest
    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    6h 46m
    $86–405

  3. Bus, drive

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    16h 49m
    $119–192

  4. Drive  648.5 mi

    1. Drive from Des Moines to Lexingtoncar car 648.5 mi
    11h 15m
    $119–171

  5. Fly to Louisville International Airport, drive

    1. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 22m
    $143–744

  6. Bus, taxi, drive

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Paoli Walmartbus bus
    3. Take the taxi from Paoli Walmart to Indiana University Southeasttaxi taxi
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    18h 29m
    $237–387

Des Moines (DSM) to Covington (CVG) flights

Calendar116Weekly Planes
Duration4h 32mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Lexington.ExpandLaunch map view
  • Distance: 592.1 mi
  • Duration: 5h 8m

What companies run services between Des Moines, IA, USA and Lexington, KY, USA?

United Airlines, American Airlines, and Delta fly from Des Moines (DSM) to Blue Grass Airport (LEX) hourly.

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