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How to get fromDes Moines to Lisleby plane, train, bus, car, or bus (Greyhound)

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There are 6 ways to get from Des Moines to Lisle by plane, train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport, train

    best
    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2. Take the train from Chicago Union Station to Lisletrain train
    3h 37m
    $94–482

  2. Drive 306.3 mi

    cheapest
    1. Drive from Des Moines to Lislecar car 306.3 mi
    5h 6m
    $56–81

  3. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus Greyhound US0157S
    2. Take the train from Galesburg Amtrak Station to Naperville Amtrak Stationtrain train Carl Sandburg / ...
    8h 20m
    $76–155

  4. Fly to Chicago O'Hare International Airport, train

    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the train from Chicago Union Station to Lisletrain train
    4h 5m
    $84–412

  5. Bus (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    8h 32m
    $57–105

  6. Bus via Bloomington

    1. Take the bus from Des Moines to Bloomington-Normalbus bus Greyhound US0157S
    2. Take the bus from Uptown Station to Oakbrook Mallbus bus Peoria line
    11h 3m
    $93–150

Des Moines to Lisle by bus and train

Calendar7Weekly Services
Duration8h 20mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Lisle.ExpandLaunch map view
  • Distance: 348.1 mi
  • Duration: 3h 37m

What companies run services between Des Moines, IA, USA and Lisle, IL, USA?

Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $50–100 and the journey takes 7h 5m.

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