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How to get fromDes Moines to Los Angelesby plane, bus (Greyhound), bus, train, or car

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There are 8 ways to get from Des Moines to Los Angeles by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Los Angeles International Airport

    best
    1. Fly from Des Moines (DSM) to Los Angeles International Airport (LAX)plane plane DSM - LAX
    4h 59m
    $165–684

  2. Bus

    1. Take the bus from Des Moines to Denverbus bus
    2. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus
    3. Take the bus from Las Vegas Bus Terminal to Los Angeles Union Stationbus bus
    36h 29m
    $312–524

  3. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson Lines 803 / ...
    2. Take the train from Kansas City to Los Angelestrain train Southwest Chief
    40h 50m
    $603–1,272

  4. Drive 1,682.8 mi

    1. Drive from Des Moines to Los Angelescar car 1,682.8 mi
    26h 2m
    $308–444

  5. Fly to Burbank Bob Hope Airport

    1. Fly from Des Moines (DSM) to Burbank Bob Hope Airport (BUR)plane plane DSM - BUR
    6h 55m
    $254–1,031

  6. Fly to Long Beach Airport

    1. Fly from Des Moines (DSM) to Long Beach Airport (LGB)plane plane DSM - LGB
    7h 47m
    $214–877

  7. Fly to Ontario International Airport, train

    1. Fly from Des Moines (DSM) to Ontario International Airport (ONT)plane plane DSM - ONT
    2. Take the train from Rancho Cucamonga to L.A. Union Stationtrain train
    8h 4m
    $228–885

  8. Fly to John Wayne Airport Orange County

    1. Fly from Des Moines (DSM) to John Wayne Airport Orange County (SNA)plane plane DSM - SNA
    8h 8m
    $270–1,141

Des Moines to Los Angeles by bus and foot

Calendar7Weekly Services
Duration36h 29mAverage Duration
Ticket$312Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Los Angeles.ExpandLaunch map view
  • Distance: 1,466.5 mi
  • Duration: 4h 59m

What companies run services between Des Moines, IA, USA and Los Angeles, CA, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Los Angeles International Airport (LAX) every 2 hours. Alternatively, you can take a bus from Des Moines to Los Angeles Union Station via Denver, Denver Union Station, and Las Vegas Bus Terminal in around 36h 29m.

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