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How to get fromDes Moines to Louisianaby plane, bus, train, bus (Greyhound), or car

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There are 8 ways to get from Des Moines to Louisiana by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Des Moines (DSM) to Louis Armstrong New Orleans International Airport (MSY)plane plane DSM - MSY
    4h 18m
    $179–823

  2. Fly to Shreveport

    cheapest
    1. Fly from Des Moines (DSM) to Shreveport (SHV)plane plane DSM - SHV
    5h 52m
    $119–573

  3. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus Greyhound US0157S
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train City of New Orleans
    25h 17m
    $253–544

  4. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    26h 20m
    $198–317

  5. Drive  989.2 mi

    1. Drive from Des Moines to New Orleanscar car 989.2 mi
    17h 20m
    $181–261

  6. Fly to Lafayette Regional Airport

    1. Fly from Des Moines (DSM) to Lafayette Regional Airport (LFT)plane plane DSM - LFT
    4h 52m
    $140–636

  7. Fly to Lake Charles Regional Airport

    1. Fly from Des Moines (DSM) to Lake Charles Regional Airport (LCH)plane plane DSM - LCH
    4h 52m
    $140–636

  8. Bus via Wake Village

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Texarkanabus bus
    3. Take the bus from Texarkana to Shreveport Bus Stationbus bus
    4. Take the bus from Shreveport Bus Station to New Orleans Bus Stationbus bus
    26h 40m
    $239–361

Des Moines to Louisiana by bus and train

Calendar7Weekly Services
Duration25h 17mAverage Duration
Ticket$253Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Louisiana.ExpandLaunch map view
  • Distance: 827 mi
  • Duration: 4h 18m

What companies run services between Des Moines, IA, USA and Louisiana, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Louis Armstrong New Orleans International Airport (MSY) every 3 hours. Alternatively, you can take a bus from Des Moines to New Orleans Bus Station via Kansas City, Kansas City Bus Station, and St Louis Bus Station in around 26h 20m.

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