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How to get fromDes Moines to Manchesterby plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

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There are 7 ways to get from Des Moines to Manchester by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Manchester Airport

    best
    1. Fly from Des Moines (DSM) to Manchester Airport (MHT)plane plane DSM - MHT
    6h 2m
    $179–773

  2. Fly to Boston Logan Airport, bus

    cheapest
    1. Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane plane DSM - BOS
    2. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    5h 39m
    $177–740

  3. Bus

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    4. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    31h 16m

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Bostontrain train
    3. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    31h 35m

  5. Drive 1,269.1 mi

    1. Drive from Des Moines to Manchestercar car 1,269.1 mi
    22h 49m
    $232–335

  6. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bostontrain train
    4. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    33h 41m

  7. Bus via Indianapolis

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Bostonbus bus
    4. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    37h 14m
    $229–455

Des Moines (DSM) to Manchester Airport (MHT) flights

Calendar34Weekly Planes
Duration6h 42mAverage Duration
Ticket$168Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Manchester.ExpandLaunch map view
  • Distance: 1,149.3 mi
  • Duration: 6h 2m

What companies run services between Des Moines, IA, USA and Manchester, NH, USA?

Southwest Airlines and American Airlines fly from Des Moines (DSM) to Manchester Airport (MHT) 5 times a day. Alternatively, you can take a bus from Des Moines to Manchester(Veterans Memorial Park) via Chicago Bus Station, New York Midtown, and Boston in around 31h 16m.

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