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How to get fromDes Moines to Manhattanby bus (Greyhound), car, plane, or bus

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There are 5 ways to get from Des Moines to Manhattan by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus Greyhound US0156
    2. Take the bus from Kansas City Bus Station to Manhattan KSbus bus Greyhound US0180s
    7h 40m
    $53–101

  2. Drive 302.8 mi

    1. Drive from Des Moines to Manhattancar car 302.8 mi
    5h 17m
    $56–80

  3. Fly to Manhattan Regional Airport

    1. Fly from Des Moines (DSM) to Manhattan Regional Airport (MHK)plane plane DSM - MHK
    5h
    $168–711

  4. Bus via Cameron

    1. Take the bus from Des Moines to Cameronbus bus
    2. Take the bus from Cameron to Kansas Citybus bus
    3. Take the bus from Kansas City Bus Station to Manhattan KSbus bus
    8h 55m
    $88–138

  5. Fly to Salina Municipal Airport, bus

    1. Fly from Des Moines (DSM) to Salina Municipal Airport (SLN)plane plane DSM - SLN
    2. Take the bus from Salina to Manhattan KSbus bus
    7h
    $170–706

Des Moines to Manhattan by bus (Greyhound)

Calendar5Weekly Buses
Duration7h 40mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Manhattan.ExpandLaunch map view
  • Distance: 350.8 mi
  • Duration: 7h 40m

What companies run services between Des Moines, IA, USA and Manhattan, KS, USA?

You can take a bus from Des Moines to Manhattan KS via Kansas City Bus Station in around 7h 40m. Alternatively, American Airlines and United Airlines fly from Des Moines (DSM) to Manhattan Regional Airport (MHK) every 4 hours.

Airlines
Bus operators

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